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Gilbert’s Syndrome With Diabetes Mellitus
Gilbert's syndrome (GS) could lead to the high bilirubin, and gestational diabetes mellitus might reverse this index. A primigravida with a pregnancy of 38 weeks and 4 days was identified having gestational diabetes mellitus (GDM) with Gilbert's syndrome. General laboratory tests were norm...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8298616/ https://www.ncbi.nlm.nih.gov/pubmed/34322357 http://dx.doi.org/10.7759/cureus.16557 |
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author | HAIXIA, LIU Li, Ruiman |
author_facet | HAIXIA, LIU Li, Ruiman |
author_sort | HAIXIA, LIU |
collection | PubMed |
description | Gilbert's syndrome (GS) could lead to the high bilirubin, and gestational diabetes mellitus might reverse this index. A primigravida with a pregnancy of 38 weeks and 4 days was identified having gestational diabetes mellitus (GDM) with Gilbert's syndrome. General laboratory tests were normal except mild unconjugated hyperbilirubinaemia and hyperglycemia. The delivery process was going well with completely delivered placenta and fetal membrane, and I° turbid amniotic fluid. The newborn was noted to have high bilirubin level which reversed after a few days of treatment. Gilbert's syndrome is rare in obstetric practice with the virtually decreased activity of uridine diphosphate glucuronosyl transferase (UDPGT). This is the first report to confirm that pregnant women with Gilbert's syndrome and gestational diabetes could give birth normally without significant adverse symptoms, except for jaundice. |
format | Online Article Text |
id | pubmed-8298616 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-82986162021-07-27 Gilbert’s Syndrome With Diabetes Mellitus HAIXIA, LIU Li, Ruiman Cureus Internal Medicine Gilbert's syndrome (GS) could lead to the high bilirubin, and gestational diabetes mellitus might reverse this index. A primigravida with a pregnancy of 38 weeks and 4 days was identified having gestational diabetes mellitus (GDM) with Gilbert's syndrome. General laboratory tests were normal except mild unconjugated hyperbilirubinaemia and hyperglycemia. The delivery process was going well with completely delivered placenta and fetal membrane, and I° turbid amniotic fluid. The newborn was noted to have high bilirubin level which reversed after a few days of treatment. Gilbert's syndrome is rare in obstetric practice with the virtually decreased activity of uridine diphosphate glucuronosyl transferase (UDPGT). This is the first report to confirm that pregnant women with Gilbert's syndrome and gestational diabetes could give birth normally without significant adverse symptoms, except for jaundice. Cureus 2021-07-22 /pmc/articles/PMC8298616/ /pubmed/34322357 http://dx.doi.org/10.7759/cureus.16557 Text en Copyright © 2021, HAIXIA et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Internal Medicine HAIXIA, LIU Li, Ruiman Gilbert’s Syndrome With Diabetes Mellitus |
title | Gilbert’s Syndrome With Diabetes Mellitus |
title_full | Gilbert’s Syndrome With Diabetes Mellitus |
title_fullStr | Gilbert’s Syndrome With Diabetes Mellitus |
title_full_unstemmed | Gilbert’s Syndrome With Diabetes Mellitus |
title_short | Gilbert’s Syndrome With Diabetes Mellitus |
title_sort | gilbert’s syndrome with diabetes mellitus |
topic | Internal Medicine |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8298616/ https://www.ncbi.nlm.nih.gov/pubmed/34322357 http://dx.doi.org/10.7759/cureus.16557 |
work_keys_str_mv | AT haixialiu gilbertssyndromewithdiabetesmellitus AT liruiman gilbertssyndromewithdiabetesmellitus |