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Gilbert’s Syndrome With Diabetes Mellitus

Gilbert's syndrome (GS) could lead to the high bilirubin, and gestational diabetes mellitus might reverse this index. A primigravida with a pregnancy of 38 weeks and 4 days was identified having gestational diabetes mellitus (GDM) with Gilbert's syndrome. General laboratory tests were norm...

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Detalles Bibliográficos
Autores principales: HAIXIA, LIU, Li, Ruiman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8298616/
https://www.ncbi.nlm.nih.gov/pubmed/34322357
http://dx.doi.org/10.7759/cureus.16557
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author HAIXIA, LIU
Li, Ruiman
author_facet HAIXIA, LIU
Li, Ruiman
author_sort HAIXIA, LIU
collection PubMed
description Gilbert's syndrome (GS) could lead to the high bilirubin, and gestational diabetes mellitus might reverse this index. A primigravida with a pregnancy of 38 weeks and 4 days was identified having gestational diabetes mellitus (GDM) with Gilbert's syndrome. General laboratory tests were normal except mild unconjugated hyperbilirubinaemia and hyperglycemia. The delivery process was going well with completely delivered placenta and fetal membrane, and I° turbid amniotic fluid. The newborn was noted to have high bilirubin level which reversed after a few days of treatment. Gilbert's syndrome is rare in obstetric practice with the virtually decreased activity of uridine diphosphate glucuronosyl transferase (UDPGT). This is the first report to confirm that pregnant women with Gilbert's syndrome and gestational diabetes could give birth normally without significant adverse symptoms, except for jaundice.
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spelling pubmed-82986162021-07-27 Gilbert’s Syndrome With Diabetes Mellitus HAIXIA, LIU Li, Ruiman Cureus Internal Medicine Gilbert's syndrome (GS) could lead to the high bilirubin, and gestational diabetes mellitus might reverse this index. A primigravida with a pregnancy of 38 weeks and 4 days was identified having gestational diabetes mellitus (GDM) with Gilbert's syndrome. General laboratory tests were normal except mild unconjugated hyperbilirubinaemia and hyperglycemia. The delivery process was going well with completely delivered placenta and fetal membrane, and I° turbid amniotic fluid. The newborn was noted to have high bilirubin level which reversed after a few days of treatment. Gilbert's syndrome is rare in obstetric practice with the virtually decreased activity of uridine diphosphate glucuronosyl transferase (UDPGT). This is the first report to confirm that pregnant women with Gilbert's syndrome and gestational diabetes could give birth normally without significant adverse symptoms, except for jaundice. Cureus 2021-07-22 /pmc/articles/PMC8298616/ /pubmed/34322357 http://dx.doi.org/10.7759/cureus.16557 Text en Copyright © 2021, HAIXIA et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
HAIXIA, LIU
Li, Ruiman
Gilbert’s Syndrome With Diabetes Mellitus
title Gilbert’s Syndrome With Diabetes Mellitus
title_full Gilbert’s Syndrome With Diabetes Mellitus
title_fullStr Gilbert’s Syndrome With Diabetes Mellitus
title_full_unstemmed Gilbert’s Syndrome With Diabetes Mellitus
title_short Gilbert’s Syndrome With Diabetes Mellitus
title_sort gilbert’s syndrome with diabetes mellitus
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8298616/
https://www.ncbi.nlm.nih.gov/pubmed/34322357
http://dx.doi.org/10.7759/cureus.16557
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