Myocardial and Pericardial Toxicity Associated With Immune Checkpoint Inhibitors in Cancer Patients

We recount a single-center experience with cardiac immunity-related adverse effects in patients treated with immune checkpoint inhibitors. Of 2,830 patients, 9 patients (0.3%) developed cardiac immunity-related adverse effects (4 cases of cardiomyopathies, 2 of myocarditis, 2 of acute pericarditis,...

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Autores principales: Chahine, Johnny, Collier, Patrick, Maroo, Anjli, Tang, W.H. Wilson, Klein, Allan L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Mini-Focus Issue: Myocardial and Pericardial Inflammation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8298653/
https://www.ncbi.nlm.nih.gov/pubmed/34317203
http://dx.doi.org/10.1016/j.jaccas.2019.11.080
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author Chahine, Johnny
Collier, Patrick
Maroo, Anjli
Tang, W.H. Wilson
Klein, Allan L.
author_facet Chahine, Johnny
Collier, Patrick
Maroo, Anjli
Tang, W.H. Wilson
Klein, Allan L.
author_sort Chahine, Johnny
collection PubMed
description We recount a single-center experience with cardiac immunity-related adverse effects in patients treated with immune checkpoint inhibitors. Of 2,830 patients, 9 patients (0.3%) developed cardiac immunity-related adverse effects (4 cases of cardiomyopathies, 2 of myocarditis, 2 of acute pericarditis, and 1 of large pericardial effusion). Disease profiles, hospital courses, and outcomes are reported. (Level of Difficulty: Advanced.)
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spelling pubmed-82986532021-07-26 Myocardial and Pericardial Toxicity Associated With Immune Checkpoint Inhibitors in Cancer Patients Chahine, Johnny Collier, Patrick Maroo, Anjli Tang, W.H. Wilson Klein, Allan L. JACC Case Rep Mini-Focus Issue: Myocardial and Pericardial Inflammation We recount a single-center experience with cardiac immunity-related adverse effects in patients treated with immune checkpoint inhibitors. Of 2,830 patients, 9 patients (0.3%) developed cardiac immunity-related adverse effects (4 cases of cardiomyopathies, 2 of myocarditis, 2 of acute pericarditis, and 1 of large pericardial effusion). Disease profiles, hospital courses, and outcomes are reported. (Level of Difficulty: Advanced.) Elsevier 2020-02-19 /pmc/articles/PMC8298653/ /pubmed/34317203 http://dx.doi.org/10.1016/j.jaccas.2019.11.080 Text en © 2020 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Mini-Focus Issue: Myocardial and Pericardial Inflammation
Chahine, Johnny
Collier, Patrick
Maroo, Anjli
Tang, W.H. Wilson
Klein, Allan L.
Myocardial and Pericardial Toxicity Associated With Immune Checkpoint Inhibitors in Cancer Patients
title Myocardial and Pericardial Toxicity Associated With Immune Checkpoint Inhibitors in Cancer Patients
title_full Myocardial and Pericardial Toxicity Associated With Immune Checkpoint Inhibitors in Cancer Patients
title_fullStr Myocardial and Pericardial Toxicity Associated With Immune Checkpoint Inhibitors in Cancer Patients
title_full_unstemmed Myocardial and Pericardial Toxicity Associated With Immune Checkpoint Inhibitors in Cancer Patients
title_short Myocardial and Pericardial Toxicity Associated With Immune Checkpoint Inhibitors in Cancer Patients
title_sort myocardial and pericardial toxicity associated with immune checkpoint inhibitors in cancer patients
topic Mini-Focus Issue: Myocardial and Pericardial Inflammation
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8298653/
https://www.ncbi.nlm.nih.gov/pubmed/34317203
http://dx.doi.org/10.1016/j.jaccas.2019.11.080
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