Cargando…

Semi-Supervised Support Vector Machine for Digital Twins Based Brain Image Fusion

The purpose is to explore the feature recognition, diagnosis, and forecasting performances of Semi-Supervised Support Vector Machines (S3VMs) for brain image fusion Digital Twins (DTs). Both unlabeled and labeled data are used regarding many unlabeled data in brain images, and semi supervised suppor...

Descripción completa

Detalles Bibliográficos
Autores principales: Wan, Zhibo, Dong, Youqiang, Yu, Zengchen, Lv, Haibin, Lv, Zhihan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8298822/
https://www.ncbi.nlm.nih.gov/pubmed/34305523
http://dx.doi.org/10.3389/fnins.2021.705323
_version_ 1783726133632565248
author Wan, Zhibo
Dong, Youqiang
Yu, Zengchen
Lv, Haibin
Lv, Zhihan
author_facet Wan, Zhibo
Dong, Youqiang
Yu, Zengchen
Lv, Haibin
Lv, Zhihan
author_sort Wan, Zhibo
collection PubMed
description The purpose is to explore the feature recognition, diagnosis, and forecasting performances of Semi-Supervised Support Vector Machines (S3VMs) for brain image fusion Digital Twins (DTs). Both unlabeled and labeled data are used regarding many unlabeled data in brain images, and semi supervised support vector machine (SVM) is proposed. Meantime, the AlexNet model is improved, and the brain images in real space are mapped to virtual space by using digital twins. Moreover, a diagnosis and prediction model of brain image fusion digital twins based on semi supervised SVM and improved AlexNet is constructed. Magnetic Resonance Imaging (MRI) data from the Brain Tumor Department of a Hospital are collected to test the performance of the constructed model through simulation experiments. Some state-of-art models are included for performance comparison: Long Short-Term Memory (LSTM), Convolutional Neural Network (CNN), Recurrent Neural Network (RNN), AlexNet, and Multi-Layer Perceptron (MLP). Results demonstrate that the proposed model can provide a feature recognition and extraction accuracy of 92.52%, at least an improvement of 2.76% compared to other models. Its training lasts for about 100 s, and the test takes about 0.68 s. The Root Mean Square Error (RMSE) and Mean Absolute Error (MAE) of the proposed model are 4.91 and 5.59%, respectively. Regarding the assessment indicators of brain image segmentation and fusion, the proposed model can provide a 79.55% Jaccard coefficient, a 90.43% Positive Predictive Value (PPV), a 73.09% Sensitivity, and a 75.58% Dice Similarity Coefficient (DSC), remarkably better than other models. Acceleration efficiency analysis suggests that the improved AlexNet model is suitable for processing massive brain image data with a higher speedup indicator. To sum up, the constructed model can provide high accuracy, good acceleration efficiency, and excellent segmentation and recognition performances while ensuring low errors, which can provide an experimental basis for brain image feature recognition and digital diagnosis.
format Online
Article
Text
id pubmed-8298822
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Frontiers Media S.A.
record_format MEDLINE/PubMed
spelling pubmed-82988222021-07-24 Semi-Supervised Support Vector Machine for Digital Twins Based Brain Image Fusion Wan, Zhibo Dong, Youqiang Yu, Zengchen Lv, Haibin Lv, Zhihan Front Neurosci Neuroscience The purpose is to explore the feature recognition, diagnosis, and forecasting performances of Semi-Supervised Support Vector Machines (S3VMs) for brain image fusion Digital Twins (DTs). Both unlabeled and labeled data are used regarding many unlabeled data in brain images, and semi supervised support vector machine (SVM) is proposed. Meantime, the AlexNet model is improved, and the brain images in real space are mapped to virtual space by using digital twins. Moreover, a diagnosis and prediction model of brain image fusion digital twins based on semi supervised SVM and improved AlexNet is constructed. Magnetic Resonance Imaging (MRI) data from the Brain Tumor Department of a Hospital are collected to test the performance of the constructed model through simulation experiments. Some state-of-art models are included for performance comparison: Long Short-Term Memory (LSTM), Convolutional Neural Network (CNN), Recurrent Neural Network (RNN), AlexNet, and Multi-Layer Perceptron (MLP). Results demonstrate that the proposed model can provide a feature recognition and extraction accuracy of 92.52%, at least an improvement of 2.76% compared to other models. Its training lasts for about 100 s, and the test takes about 0.68 s. The Root Mean Square Error (RMSE) and Mean Absolute Error (MAE) of the proposed model are 4.91 and 5.59%, respectively. Regarding the assessment indicators of brain image segmentation and fusion, the proposed model can provide a 79.55% Jaccard coefficient, a 90.43% Positive Predictive Value (PPV), a 73.09% Sensitivity, and a 75.58% Dice Similarity Coefficient (DSC), remarkably better than other models. Acceleration efficiency analysis suggests that the improved AlexNet model is suitable for processing massive brain image data with a higher speedup indicator. To sum up, the constructed model can provide high accuracy, good acceleration efficiency, and excellent segmentation and recognition performances while ensuring low errors, which can provide an experimental basis for brain image feature recognition and digital diagnosis. Frontiers Media S.A. 2021-07-09 /pmc/articles/PMC8298822/ /pubmed/34305523 http://dx.doi.org/10.3389/fnins.2021.705323 Text en Copyright © 2021 Wan, Dong, Yu, Lv and Lv. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neuroscience
Wan, Zhibo
Dong, Youqiang
Yu, Zengchen
Lv, Haibin
Lv, Zhihan
Semi-Supervised Support Vector Machine for Digital Twins Based Brain Image Fusion
title Semi-Supervised Support Vector Machine for Digital Twins Based Brain Image Fusion
title_full Semi-Supervised Support Vector Machine for Digital Twins Based Brain Image Fusion
title_fullStr Semi-Supervised Support Vector Machine for Digital Twins Based Brain Image Fusion
title_full_unstemmed Semi-Supervised Support Vector Machine for Digital Twins Based Brain Image Fusion
title_short Semi-Supervised Support Vector Machine for Digital Twins Based Brain Image Fusion
title_sort semi-supervised support vector machine for digital twins based brain image fusion
topic Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8298822/
https://www.ncbi.nlm.nih.gov/pubmed/34305523
http://dx.doi.org/10.3389/fnins.2021.705323
work_keys_str_mv AT wanzhibo semisupervisedsupportvectormachinefordigitaltwinsbasedbrainimagefusion
AT dongyouqiang semisupervisedsupportvectormachinefordigitaltwinsbasedbrainimagefusion
AT yuzengchen semisupervisedsupportvectormachinefordigitaltwinsbasedbrainimagefusion
AT lvhaibin semisupervisedsupportvectormachinefordigitaltwinsbasedbrainimagefusion
AT lvzhihan semisupervisedsupportvectormachinefordigitaltwinsbasedbrainimagefusion