Restoration of the ATG5-dependent autophagy sensitizes DU145 prostate cancer cells to chemotherapeutic drugs

Autophagy serves an important role in cancer cell survival and drug resistance. In the present study, the prostate cancer DU145 cell line was used, which lacks autophagy related 5 (ATG5) expression and is defective in induction of ATG5-dependent autophagy. The aim of the study was to examine the eff...

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Detalles Bibliográficos
Autores principales: Peng, Ke, Sun, Aiqin, Zhu, Jun, Gao, Jinyi, Li, Yanlin, Shao, Genbao, Yang, Wannian, Lin, Qiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8298997/
https://www.ncbi.nlm.nih.gov/pubmed/34386060
http://dx.doi.org/10.3892/ol.2021.12899

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8298997/
https://www.ncbi.nlm.nih.gov/pubmed/34386060
http://dx.doi.org/10.3892/ol.2021.12899

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