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PPM-18, an Analog of Vitamin K, Induces Autophagy and Apoptosis in Bladder Cancer Cells Through ROS and AMPK Signaling Pathways

PPM-18, identified as a novel analog of vitamin K, has been reported to play a critical role in the suppression of seizures. However, the concerns that whether PPM-18, like vitamin K, exerts anticancer activity remain to be further investigated. Here, we found that PPM-18 remarkably suppressed the p...

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Detalles Bibliográficos
Autores principales: Lu, Huiai, Mei, Chunlei, Yang, Luhao, Zheng, Junyan, Tong, Junwei, Duan, Fengsen, Liang, Huageng, Hong, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8299005/
https://www.ncbi.nlm.nih.gov/pubmed/34305598
http://dx.doi.org/10.3389/fphar.2021.684915