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Iron regulatory protein 1 promotes ferroptosis by sustaining cellular iron homeostasis in melanoma
Melanoma, the most aggressive skin cancer, is mainly treated with BRAF inhibitors or immunotheareapy. However, most patients who initially responded to BRAF inhibitors or immunotheareapy become resistant following relapse. Ferroptosis is a form of regulated cell death characterized by its dependence...
Autores principales: | Yao, Fengping, Cui, Xiaohong, Zhang, Ying, Bei, Zhuchun, Wang, Hongquan, Zhao, Dongxu, Wang, Hong, Yang, Yongfei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8299017/ https://www.ncbi.nlm.nih.gov/pubmed/34386079 http://dx.doi.org/10.3892/ol.2021.12918 |
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