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Iron regulatory protein 1 promotes ferroptosis by sustaining cellular iron homeostasis in melanoma

Melanoma, the most aggressive skin cancer, is mainly treated with BRAF inhibitors or immunotheareapy. However, most patients who initially responded to BRAF inhibitors or immunotheareapy become resistant following relapse. Ferroptosis is a form of regulated cell death characterized by its dependence...

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Detalles Bibliográficos
Autores principales: Yao, Fengping, Cui, Xiaohong, Zhang, Ying, Bei, Zhuchun, Wang, Hongquan, Zhao, Dongxu, Wang, Hong, Yang, Yongfei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8299017/
https://www.ncbi.nlm.nih.gov/pubmed/34386079
http://dx.doi.org/10.3892/ol.2021.12918

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