Cargando…

The Association Between STX1B Polymorphisms and Treatment Response in Patients With Epilepsy

Background: Epilepsy is a debilitating brain disease with complex inheritance and frequent treatment resistance. However, the role of STX1B single nucleotide polymorphisms (SNPs) in epilepsy treatment remains unknown. Objective: This study aimed to explore the genetic association of STX1B SNPs with...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Shitao, Zhou, Liang, He, Chenglu, Wang, Dan, Cai, Xuemei, Yu, Yanying, Chen, Liling, Lu, Di, Bian, Ligong, Du, Sunbing, Wu, Qian, Han, Yanbing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8299048/ https://www.ncbi.nlm.nih.gov/pubmed/34305610 http://dx.doi.org/10.3389/fphar.2021.701575

Ejemplares similares

A novel BCL11A polymorphism influences gene expression, therapeutic response and epilepsy risk: A multicenter study
por: Wang, Shitao, et al.
Publicado: (2022)

Identification of the ZEB2 gene as a potential target for epilepsy therapy and the association between rs10496964 and ZEB2 expression
por: Wang, Shitao, et al.
Publicado: (2021)

Analysis of GABRG2 C588T polymorphism in genetic epilepsy and evaluation of GABRG2 in drug treatment
por: Wang, Shitao, et al.
Publicado: (2021)

Alzheimer’s disease and epilepsy: An increasingly recognized comorbidity
por: Yang, Fei, et al.
Publicado: (2022)

Mechanisms that Determine the Differential Stability of Stx(+) and Stx(−) Lysogens
por: Colon, Michael P., et al.
Publicado: (2016)

STX1B-related epilepsy in a 24-month-old female infant
por: Burghardt, Katharina, et al.
Publicado: (2020)

Association of the ADORA2A receptor and CD73 polymorphisms with epilepsy
por: Shi, Nan-Rui, et al.
Publicado: (2023)

Biodistribution and elimination kinetics of systemic Stx2 by the Stx2A and Stx2B subunit-specific human monoclonal antibodies in mice
por: Sheoran, Abhineet, et al.
Publicado: (2012)

Switching Shiga Toxin (Stx) Type from Stx2d to Stx2a but Not Stx2c Alters Virulence of Stx-Producing Escherichia coli (STEC) Strain B2F1 in Streptomycin (Str)-Treated Mice
por: McNichol, Beth A., et al.
Publicado: (2021)

Natural Medicines for the Treatment of Epilepsy: Bioactive Components, Pharmacology and Mechanism
por: He, Li-Ying, et al.
Publicado: (2021)

New Stx2e Monoclonal Antibodies for Immunological Detection and Distinction of Stx2 Subtypes
por: Skinner, Craig, et al.
Publicado: (2015)

Detection of stx(1) and stx(2) Genes in Pennsylvanian White-Tailed Deer
por: Kistler, Whitney M., et al.
Publicado: (2011)

Synergistic association of STX1A and VAMP2 with cryptogenic epilepsy in North Indian population
por: Baghel, Ruchi, et al.
Publicado: (2016)

Heterozygous and homozygous variants in STX1A cause a neurodevelopmental disorder with or without epilepsy
por: Luppe, Johannes, et al.
Publicado: (2022)

Reduced Toxicity of Shiga Toxin (Stx) Type 2c in Mice Compared to Stx2d Is Associated with Instability of Stx2c Holotoxin
por: Bunger, Joshua C., et al.
Publicado: (2015)

Identification and Characterization of ten Escherichia coli Strains Encoding Novel Shiga Toxin 2 Subtypes, Stx2n as Well as Stx2j, Stx2m, and Stx2o, in the United States
por: Lindsey, Rebecca L., et al.
Publicado: (2023)

Differences in the Shiga Toxin (Stx) 2a Phage Regulatory Switch Region Influence Stx2 Localization and Virulence of Stx-Producing Escherichia coli in Mice
por: Atitkar, Rama R., et al.
Publicado: (2023)

Pharmacogenetics-based population pharmacokinetic analysis and dose optimization of valproic acid in Chinese southern children with epilepsy: Effect of ABCB1 gene polymorphism
por: Shen, Xianhuan, et al.
Publicado: (2022)

Impact of GGCX, STX1B and FPGS Polymorphisms on Warfarin Dose Requirements in European‐Americans and Egyptians
por: Hamadeh, IS, et al.
Publicado: (2016)

Shiga Toxin (Stx) Type 1a Reduces the Oral Toxicity of Stx Type 2a
por: Russo, Lisa M., et al.
Publicado: (2016)

Dose-Effect Relationship of Chitosan and Danshen Combined Injection for Fallopian Tube Recanalization
por: Huang, Chen, et al.
Publicado: (2022)

STxB as an Antigen Delivery Tool for Mucosal Vaccination
por: Tartour, Eric, et al.
Publicado: (2022)

Engineered Synthetic STxB for Enhanced Cytosolic Delivery
por: Hadjerci, Justine, et al.
Publicado: (2023)

Anti-Epileptic Effect of Crocin on Experimental Temporal Lobe Epilepsy in Mice
por: Zhong, Kai, et al.
Publicado: (2022)

New High-Affinity Monoclonal Antibodies against Shiga Toxin 1 Facilitate the Detection of Hybrid Stx1/Stx2 In Vivo
por: Skinner, Craig, et al.
Publicado: (2014)

Cannabidiol Treatment for Refractory Epilepsies in Pediatrics
por: Raucci, Umberto, et al.
Publicado: (2020)

Improving Therapy of Pharmacoresistant Epilepsies: The Role of Fenfluramine
por: Dini, Gianluca, et al.
Publicado: (2022)

Polymorphisms of ACMSD-TMEM163, MCCC1, and BCKDK-STX1B Are Not Associated with Parkinson's Disease in Taiwan
por: Chang, Kuo-Hsuan, et al.
Publicado: (2019)

Astragaloside IV Alleviates Intestinal Barrier Dysfunction via the AKT-GSK3β-β-Catenin Pathway in Peritoneal Dialysis
por: He, Jiaqi, et al.
Publicado: (2022)

Targeting ferroptosis as novel therapeutic approaches for epilepsy
por: Jin, Yuzi, et al.
Publicado: (2023)

Comparison of the effectiveness and safety of perampanel and oxcarbazepine as monotherapy in children and adolescents with newly diagnosed focal epilepsy
por: Yi, Jia-Qin, et al.
Publicado: (2023)

The Efficacy and Safety of Roxadustat for Anemia in Patients With Chronic Kidney Disease: A Meta-Analysis
por: Wang, Lijun, et al.
Publicado: (2022)

Corrigendum: Improving therapy of pharmacoresistant epilepsies: The role of fenfluramine
por: Dini, Gianluca, et al.
Publicado: (2023)

Promoter Sequence of Shiga Toxin 2 (Stx2) Is Recognized In Vivo, Leading to Production of Biologically Active Stx2
por: Bentancor, Leticia V., et al.
Publicado: (2013)

Corrigendum: Comparison of the effectiveness and safety of perampanel and oxcarbazepine as monotherapy in children and adolescents with newly diagnosed focal epilepsy
por: Yi, Jia-Qin, et al.
Publicado: (2023)

Polysaccharides, Next Potential Agent for the Treatment of Epilepsy?
por: Xie, Xuemin, et al.
Publicado: (2022)

Clinical spectrum of STX1B-related epileptic disorders
por: Wolking, Stefan, et al.
Publicado: (2019)

Salvianolic Acids: Potential Source of Natural Drugs for the Treatment of Fibrosis Disease and Cancer
por: Ma, Lunkun, et al.
Publicado: (2019)

MicroRNA-221-3p Suppresses the Microglia Activation and Seizures by Inhibiting of HIF-1α in Valproic Acid-Resistant Epilepsy
por: Fu, Meng, et al.
Publicado: (2021)

Monoclonal Antibody Therapy in Neuromyelitis Optica Spectrum Disorders: a Meta-analysis of Randomized Control Trials
por: Kong, Fanxin, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_3ta144nc93t0ps2ijrul0mq1k3