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Identification and evaluation of potential SARS-CoV-2 antiviral agents targeting mRNA cap guanine N7-Methyltransferase

SARS-CoV-2, the cause of the currently ongoing COVID-19 pandemic, encodes its own mRNA capping machinery. Insights into this capping system may provide new ideas for therapeutic interventions and drug discovery. In this work, we employ a previously developed Py-FLINT screening approach to study the...

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Detalles Bibliográficos
Autores principales:	Kasprzyk, Renata, Spiewla, Tomasz J., Smietanski, Miroslaw, Golojuch, Sebastian, Vangeel, Laura, De Jonghe, Steven, Jochmans, Dirk, Neyts, Johan, Kowalska, Joanna, Jemielity, Jacek
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Authors. Published by Elsevier B.V. 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8299157/ https://www.ncbi.nlm.nih.gov/pubmed/34303749 http://dx.doi.org/10.1016/j.antiviral.2021.105142

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