Impaired local intrinsic immunity to SARS-CoV-2 infection in severe COVID-19

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SARS-CoV-2 infection can cause severe respiratory COVID-19. However, many individuals present with isolated upper respiratory symptoms, suggesting potential to constrain viral pathology to the nasopharynx. Which cells SARS-CoV-2 primarily targets and how infection influences the respiratory epitheli...

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Detalles Bibliográficos
Autores principales: Ziegler, Carly G.K., Miao, Vincent N., Owings, Anna H., Navia, Andrew W., Tang, Ying, Bromley, Joshua D., Lotfy, Peter, Sloan, Meredith, Laird, Hannah, Williams, Haley B., George, Micayla, Drake, Riley S., Christian, Taylor, Parker, Adam, Sindel, Campbell B., Burger, Molly W., Pride, Yilianys, Hasan, Mohammad, Abraham, George E., Senitko, Michal, Robinson, Tanya O., Shalek, Alex K., Glover, Sarah C., Horwitz, Bruce H., Ordovas-Montanes, Jose
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8299217/
https://www.ncbi.nlm.nih.gov/pubmed/34352228
http://dx.doi.org/10.1016/j.cell.2021.07.023
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