MFP1/MSD-1 and MFP2/NSPH-2 co-localize with MSP during C. elegans spermatogenesis

Until recently, the only verified component of Fibrous Bodies (FBs) within Caenorhabditis elegans spermatocytes was the Major Sperm Protein (MSP), a nematode-specific cytoskeletal element. Earlier studies in the pig parasite Ascaris suum had identified accessory proteins that facilitate MSP polymeri...

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Autores principales: Morrison, Kayleigh N., Uyehara, Christopher M., Ragle, James Matthew, Ward, Jordan D., Shakes, Diane C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Caltech Library 2021
Materias:
New Finding
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8299296/
https://www.ncbi.nlm.nih.gov/pubmed/34316545
http://dx.doi.org/10.17912/micropub.biology.000427
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author Morrison, Kayleigh N.
Uyehara, Christopher M.
Ragle, James Matthew
Ward, Jordan D.
Shakes, Diane C.
author_facet Morrison, Kayleigh N.
Uyehara, Christopher M.
Ragle, James Matthew
Ward, Jordan D.
Shakes, Diane C.
author_sort Morrison, Kayleigh N.
collection PubMed
description Until recently, the only verified component of Fibrous Bodies (FBs) within Caenorhabditis elegans spermatocytes was the Major Sperm Protein (MSP), a nematode-specific cytoskeletal element. Earlier studies in the pig parasite Ascaris suum had identified accessory proteins that facilitate MSP polymerization and depolymerization within the pseudopod of crawling spermatozoa. In this study, we show that C. elegans homologs of the two Ascaris accessory proteins MFP1 and MFP2 co-localize with MSP in both the pseudopods of C. elegans sperm and the FBs of C. elegans spermatocytes.
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spelling pubmed-82992962021-07-26 MFP1/MSD-1 and MFP2/NSPH-2 co-localize with MSP during C. elegans spermatogenesis Morrison, Kayleigh N. Uyehara, Christopher M. Ragle, James Matthew Ward, Jordan D. Shakes, Diane C. MicroPubl Biol New Finding Until recently, the only verified component of Fibrous Bodies (FBs) within Caenorhabditis elegans spermatocytes was the Major Sperm Protein (MSP), a nematode-specific cytoskeletal element. Earlier studies in the pig parasite Ascaris suum had identified accessory proteins that facilitate MSP polymerization and depolymerization within the pseudopod of crawling spermatozoa. In this study, we show that C. elegans homologs of the two Ascaris accessory proteins MFP1 and MFP2 co-localize with MSP in both the pseudopods of C. elegans sperm and the FBs of C. elegans spermatocytes. Caltech Library 2021-07-22 /pmc/articles/PMC8299296/ /pubmed/34316545 http://dx.doi.org/10.17912/micropub.biology.000427 Text en Copyright: © 2021 by the authors https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle New Finding
Morrison, Kayleigh N.
Uyehara, Christopher M.
Ragle, James Matthew
Ward, Jordan D.
Shakes, Diane C.
MFP1/MSD-1 and MFP2/NSPH-2 co-localize with MSP during C. elegans spermatogenesis
title MFP1/MSD-1 and MFP2/NSPH-2 co-localize with MSP during C. elegans spermatogenesis
title_full MFP1/MSD-1 and MFP2/NSPH-2 co-localize with MSP during C. elegans spermatogenesis
title_fullStr MFP1/MSD-1 and MFP2/NSPH-2 co-localize with MSP during C. elegans spermatogenesis
title_full_unstemmed MFP1/MSD-1 and MFP2/NSPH-2 co-localize with MSP during C. elegans spermatogenesis
title_short MFP1/MSD-1 and MFP2/NSPH-2 co-localize with MSP during C. elegans spermatogenesis
title_sort mfp1/msd-1 and mfp2/nsph-2 co-localize with msp during c. elegans spermatogenesis
topic New Finding
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8299296/
https://www.ncbi.nlm.nih.gov/pubmed/34316545
http://dx.doi.org/10.17912/micropub.biology.000427
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