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Prediction of Minocycline Activity in the Gut From a Pig Preclinical Model Using a Pharmacokinetic -Pharmacodynamic Approach

The increase of multidrug-resistant (MDR) bacteria has renewed interest in old antibiotics, such as minocycline, that can be active against various MDR Gram-negative pathogens. The elimination of minocycline by both kidneys and liver makes it suitable for impaired renal function patients. However, t...

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Detalles Bibliográficos
Autores principales:	Vallé, Quentin, Roques, Béatrice B., Bousquet-Mélou, Alain, Dahlhaus, David, Ramon-Portugal, Felipe, Dupouy, Véronique, Bibbal, Delphine, Ferran, Aude A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8299485/ https://www.ncbi.nlm.nih.gov/pubmed/34305836 http://dx.doi.org/10.3389/fmicb.2021.671376

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