A Pan-Cancer Analysis of CD161, a Potential New Immune Checkpoint

BACKGROUND: CD161, encoded by killer cell lectin-like receptor B1 gene, is a newly reported candidate inhibitor of tumour-infiltrating T cells. Antibody-mediated CD161 blockade enhances T cell-mediated killing of cancer cells in vitro and in vivo in several tumour types. We evaluated the role of CD1...

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Detalles Bibliográficos
Autores principales: Zhou, Xiaohan, Du, Jun, Liu, Chengdong, Zeng, Hanyi, Chen, Yuting, Liu, Li, Wu, Dehua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8299557/
https://www.ncbi.nlm.nih.gov/pubmed/34305920
http://dx.doi.org/10.3389/fimmu.2021.688215

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8299557/
https://www.ncbi.nlm.nih.gov/pubmed/34305920
http://dx.doi.org/10.3389/fimmu.2021.688215

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