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A Pan-Cancer Analysis of CD161, a Potential New Immune Checkpoint

BACKGROUND: CD161, encoded by killer cell lectin-like receptor B1 gene, is a newly reported candidate inhibitor of tumour-infiltrating T cells. Antibody-mediated CD161 blockade enhances T cell-mediated killing of cancer cells in vitro and in vivo in several tumour types. We evaluated the role of CD1...

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Detalles Bibliográficos
Autores principales:	Zhou, Xiaohan, Du, Jun, Liu, Chengdong, Zeng, Hanyi, Chen, Yuting, Liu, Li, Wu, Dehua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8299557/ https://www.ncbi.nlm.nih.gov/pubmed/34305920 http://dx.doi.org/10.3389/fimmu.2021.688215

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