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Up-regulation of microRNA-135 or silencing of PCSK6 attenuates inflammatory response in preeclampsia by restricting NLRP3 inflammasome

OBJECTIVE: Numerous studies have confirmed the correlation of microRNAs (miRNAs) with human disease, yet few have explored the role of miR-135 in preeclampsia (PE). This study intends to discuss miR-135’s function in inflammatory response in PE by modulating proprotein convertase subtilisin/kexin-6...

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Detalles Bibliográficos
Autores principales: Zhao, Xiaolan, Zhang, Xun, Wu, Zhao, Mei, Jie, Li, Lingling, Wang, Yujue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8299578/
https://www.ncbi.nlm.nih.gov/pubmed/34301174
http://dx.doi.org/10.1186/s10020-021-00335-x