Cargando…

Up-regulation of microRNA-135 or silencing of PCSK6 attenuates inflammatory response in preeclampsia by restricting NLRP3 inflammasome

OBJECTIVE: Numerous studies have confirmed the correlation of microRNAs (miRNAs) with human disease, yet few have explored the role of miR-135 in preeclampsia (PE). This study intends to discuss miR-135’s function in inflammatory response in PE by modulating proprotein convertase subtilisin/kexin-6...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhao, Xiaolan, Zhang, Xun, Wu, Zhao, Mei, Jie, Li, Lingling, Wang, Yujue
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8299578/ https://www.ncbi.nlm.nih.gov/pubmed/34301174 http://dx.doi.org/10.1186/s10020-021-00335-x

Ejemplares similares

Long non-coding RNA OIP5-AS1 suppresses microRNA-92a to augment proliferation and metastasis of ovarian cancer cells through upregulating ITGA6
por: Wang, Yujue, et al.
Publicado: (2022)

Role of the NLRP3 Inflammasome in Preeclampsia
por: Shirasuna, Koumei, et al.
Publicado: (2020)

Interactions between PCSK9 and NLRP3 inflammasome signaling in atherosclerosis
por: Wang, Yanan, et al.
Publicado: (2023)

NLRP3 inflammasome via IL-1β regulates PCSK9 secretion
por: Ding, Zufeng, et al.
Publicado: (2020)

MicroRNA Post-transcriptional Regulation of the NLRP3 Inflammasome in Immunopathologies
por: Tezcan, Gulcin, et al.
Publicado: (2019)

The NLRP3 Inflammasome Role in the Pathogenesis of Pregnancy Induced Hypertension and Preeclampsia
por: Socha, Maciej W., et al.
Publicado: (2020)

NLRP3 inflammasome via IL-1β regulates PCSK9 secretion: Erratum
por: Ding, Zufeng, et al.
Publicado: (2022)

The Impact of Melatonin and NLRP3 Inflammasome on the Expression of microRNAs in Aged Muscle
por: Sayed, Ramy KA, et al.
Publicado: (2021)

The caspase-1 inhibitor AC-YVAD-CMK attenuates acute gastric injury in mice: involvement of silencing NLRP3 inflammasome activities
por: Zhang, Fang, et al.
Publicado: (2016)

Endogenous and Uric Acid-Induced Activation of NLRP3 Inflammasome in Pregnant Women with Preeclampsia
por: Matias, Mariana Leticia, et al.
Publicado: (2015)

Activation of an NLRP3 Inflammasome Restricts Mycobacterium kansasii Infection
por: Chen, Chang-Chieh, et al.
Publicado: (2012)

Silencing lncRNA ZFAS1 or elevated microRNA-135a represses proliferation, migration, invasion and resistance to apoptosis of osteosarcoma cells
por: Zhao, Zilong, et al.
Publicado: (2019)

RelA/MicroRNA-30a/NLRP3 signal axis is involved in rheumatoid arthritis via regulating NLRP3 inflammasome in macrophages
por: Yang, Qiudong, et al.
Publicado: (2021)

Silibinin Downregulates the NF-κB Pathway and NLRP1/NLRP3 Inflammasomes in Monocytes from Pregnant Women with Preeclampsia
por: Matias, Mariana Leticia, et al.
Publicado: (2019)

NLRP3 inflammasome in peripheral blood monocytes as a risk factor for early -onset preeclampsia
por: Yang, Hong, et al.
Publicado: (2023)

Annatto Tocotrienol Attenuates NLRP3 Inflammasome Activation in Macrophages
por: Buckner, Teresa, et al.
Publicado: (2017)

The effect of PCSK9 immunization on the hepatic level of microRNAs associated with the PCSK9/LDLR pathway
por: Ataei, Sarina, et al.
Publicado: (2023)

Functional role of microRNA-135a in colitis
por: Lou, Chunyan, et al.
Publicado: (2018)

TMBIM4 Deficiency Facilitates NLRP3 Inflammasome Activation-Induced Pyroptosis of Trophoblasts: A Potential Pathogenesis of Preeclampsia
por: Chen, Yuanyao, et al.
Publicado: (2023)

MicroRNA-21 Mediates the Inhibiting Effect of Praziquantel on NLRP3 Inflammasome in Schistosoma japonicum Infection
por: Kong, Delong, et al.
Publicado: (2020)

Naoxintong attenuates Ischaemia/reperfusion Injury through inhibiting NLRP3 inflammasome activation
por: Wang, Yaqiong, et al.
Publicado: (2016)

The E3 ubiquitin ligase TRIM31 attenuates NLRP3 inflammasome activation by promoting proteasomal degradation of NLRP3
por: Song, Hui, et al.
Publicado: (2016)

microRNA-135b expression silences Ppm1e to provoke AMPK activation and inhibit osteoblastoma cell proliferation
por: Li, Zheng-Wei, et al.
Publicado: (2017)

Placentas from Women with Late-Onset Preeclampsia Exhibit Increased Expression of the NLRP3 Inflammasome Machinery
por: Garcia-Puente, Luis M., et al.
Publicado: (2023)

Circulating C19MC MicroRNAs in Preeclampsia, Gestational Hypertension, and Fetal Growth Restriction
por: Hromadnikova, Ilona, et al.
Publicado: (2013)

Fisetin Attenuates Diabetic Nephropathy-Induced Podocyte Injury by Inhibiting NLRP3 Inflammasome
por: Dong, Wenmin, et al.
Publicado: (2022)

MicroRNA-135b-5p regulates trophoblast cell function by targeting phosphoinositide-3-kinase regulatory subunit 2 in preeclampsia
por: Zhang, Xia, et al.
Publicado: (2022)

Lipoxin A4 attenuates MSU-crystal-induced NLRP3 inflammasome activation through suppressing Nrf2 thereby increasing TXNRD2
por: Zhou, You, et al.
Publicado: (2022)

Extracellular vesicle‐derived microRNA‐18b ameliorates preeclampsia by enhancing trophoblast proliferation and migration via Notch2/TIM3/mTORC1 axis
por: Yang, Zhongmei, et al.
Publicado: (2021)

NLRP3 inflammasome as a sensor of micro- and nanoplastics immunotoxicity
por: Alijagic, Andi, et al.
Publicado: (2023)

Targeting the NLRP3 inflammasome to attenuate spinal cord injury in mice
por: Jiang, Wu, et al.
Publicado: (2017)

The NLRP6 inflammasome
por: Zheng, Danping, et al.
Publicado: (2020)

Snail-regulated exosomal microRNA-21 suppresses NLRP3 inflammasome activity to enhance cisplatin resistance
por: Cheng, Han-Ying, et al.
Publicado: (2022)

Targeting PCSK9 Ameliorates Graft Vascular Disease in Mice by Inhibiting NLRP3 Inflammasome Activation in Vascular Smooth Muscle Cells
por: Zou, Yanqiang, et al.
Publicado: (2022)

MicroRNA-221 silencing attenuates the degenerated phenotype of intervertebral disc cells
por: Penolazzi, Letizia, et al.
Publicado: (2018)

microRNA-483 ameliorates hypercholesterolemia by inhibiting PCSK9 production
por: Dong, Jianjie, et al.
Publicado: (2020)

Teuvincenone F Suppresses LPS-Induced Inflammation and NLRP3 Inflammasome Activation by Attenuating NEMO Ubiquitination
por: Zhao, Xibao, et al.
Publicado: (2017)

The mitochondrial protease HtrA2 restricts the NLRP3 and AIM2 inflammasomes
por: Rodrigue-Gervais, Ian Gaël, et al.
Publicado: (2018)

NLRP3 Inflammasome Activation by MicroRNA-495 Promoter Methylation May Contribute to the Progression of Acute Lung Injury
por: Ying, Youguo, et al.
Publicado: (2019)

Apigenin attenuates atherosclerosis and non-alcoholic fatty liver disease through inhibition of NLRP3 inflammasome in mice
por: Lu, Zheng, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_mqndlqtr860qse90t4mmi7i86s