The Instability of Dimeric Fc-Fusions Expressed in Plants Can Be Solved by Monomeric Fc Technology

The potential therapeutic value of many proteins is ultimately limited by their rapid in vivo clearance. One strategy to limit clearance by metabolism and excretion, and improving the stability of therapeutic proteins, is their fusion to the immunoglobulin fragment crystallizable region (Fc). The Fc...

Descripción completa

Detalles Bibliográficos
Autores principales: Gattinger, Pia, Izadi, Shiva, Grünwald-Gruber, Clemens, Kallolimath, Somanath, Castilho, Alexandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Plant Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8299721/
https://www.ncbi.nlm.nih.gov/pubmed/34305971
http://dx.doi.org/10.3389/fpls.2021.671728

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8299721/
https://www.ncbi.nlm.nih.gov/pubmed/34305971
http://dx.doi.org/10.3389/fpls.2021.671728

Ejemplares similares