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Vaccine effectiveness against symptomatic SARS-CoV-2 infection in adults aged 65 years and older in primary care: I-MOVE-COVID-19 project, Europe, December 2020 to May 2021

We measured COVID-19 vaccine effectiveness (VE) against symptomatic SARS-CoV-2 infection at primary care/outpatient level among adults ≥ 65 years old using a multicentre test-negative design in eight European countries. We included 592 SARS-CoV-2 cases and 4,372 test-negative controls in the main an...

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Autores principales: Kissling, Esther, Hooiveld, Mariette, Sandonis Martín, Virginia, Martínez-Baz, Iván, William, Naoma, Vilcu, Ana-Maria, Mazagatos, Clara, Domegan, Lisa, de Lusignan, Simon, Meijer, Adam, Machado, Ausenda, Brytting, Mia, Casado, Itziar, Murray, Josephine-L K., Belhillil, Sylvie, Larrauri, Amparo, O’Donnell, Joan, Tsang, Ruby, de Lange, Marit, Rodrigues, Ana Paula, Riess, Maximilian, Castilla, Jesús, Hamilton, Mark, Falchi, Alessandra, Pozo, Francisco, Dunford, Linda, Cogdale, Jade, Jansen, Tessa, Guiomar, Raquel, Enkirch, Theresa, Burgui, Cristina, Sigerson, Debbie, Blanchon, Thierry, Martínez Ochoa, Eva María, Connell, Jeff, Ellis, Joanna, van Gageldonk-Lafeber, Rianne, Kislaya, Irina, Rose, Angela MC, Valenciano, Marta, Andrews, Nick, Lopez Bernal, Jamie, Whitaker, Heather, Guerrisi, Caroline, Launay, Titouan, Masse, Shirley, van der Werf, Sylvie, Enouf, Vincent, Cuddihy, John, McKenna, Adele, Joyce, Michael, de Gascun, Cillian, Moran, Joanne, Miqueleiz, Ana, Navascués, Ana, Trobajo-Sanmartín, Camino, Ezpeleta, Carmen, Moreno, Paula López, Gorricho, Javier, Ardanaz, Eva, Baigorria, Fernando, Barricarte, Aurelio, de la Cruz, Enrique, Egüés, Nerea, García Cenoz, Manuel, Guevara, Marcela, Moreno-Iribas, Conchi, Sayón, Carmen, Gomez, Verónica, Nunes, Baltazar, Roquete, Rita, Silva, Adriana, Melo, Aryse, Costa, Inês, Verdasca, Nuno, Conde, Patrícia, Marques, Diogo FP, Molesworth, Anna, Quinn, Leanne, Leyton, Miranda, Campbell, Selin, Thoulass, Janine, McMenamin, Jim, Mateo, Ana Martínez, Basile, Luca, Castrillejo, Daniel, Quiñones Rubio, Carmen, Delgado-Sanz, Concepción, Oliva., Jesús
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Centre for Disease Prevention and Control (ECDC) 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8299744/
https://www.ncbi.nlm.nih.gov/pubmed/34296676
http://dx.doi.org/10.2807/1560-7917.ES.2021.26.29.2100670
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author Kissling, Esther
Hooiveld, Mariette
Sandonis Martín, Virginia
Martínez-Baz, Iván
William, Naoma
Vilcu, Ana-Maria
Mazagatos, Clara
Domegan, Lisa
de Lusignan, Simon
Meijer, Adam
Machado, Ausenda
Brytting, Mia
Casado, Itziar
Murray, Josephine-L K.
Belhillil, Sylvie
Larrauri, Amparo
O’Donnell, Joan
Tsang, Ruby
de Lange, Marit
Rodrigues, Ana Paula
Riess, Maximilian
Castilla, Jesús
Hamilton, Mark
Falchi, Alessandra
Pozo, Francisco
Dunford, Linda
Cogdale, Jade
Jansen, Tessa
Guiomar, Raquel
Enkirch, Theresa
Burgui, Cristina
Sigerson, Debbie
Blanchon, Thierry
Martínez Ochoa, Eva María
Connell, Jeff
Ellis, Joanna
van Gageldonk-Lafeber, Rianne
Kislaya, Irina
Rose, Angela MC
Valenciano, Marta
Andrews, Nick
Lopez Bernal, Jamie
Whitaker, Heather
Guerrisi, Caroline
Launay, Titouan
Masse, Shirley
van der Werf, Sylvie
Enouf, Vincent
Cuddihy, John
McKenna, Adele
Joyce, Michael
de Gascun, Cillian
Moran, Joanne
Miqueleiz, Ana
Navascués, Ana
Trobajo-Sanmartín, Camino
Ezpeleta, Carmen
Moreno, Paula López
Gorricho, Javier
Ardanaz, Eva
Baigorria, Fernando
Barricarte, Aurelio
de la Cruz, Enrique
Egüés, Nerea
García Cenoz, Manuel
Guevara, Marcela
Moreno-Iribas, Conchi
Sayón, Carmen
Gomez, Verónica
Nunes, Baltazar
Roquete, Rita
Silva, Adriana
Melo, Aryse
Costa, Inês
Verdasca, Nuno
Conde, Patrícia
Marques, Diogo FP
Molesworth, Anna
Quinn, Leanne
Leyton, Miranda
Campbell, Selin
Thoulass, Janine
McMenamin, Jim
Mateo, Ana Martínez
Basile, Luca
Castrillejo, Daniel
Quiñones Rubio, Carmen
Delgado-Sanz, Concepción
Oliva., Jesús
author_facet Kissling, Esther
Hooiveld, Mariette
Sandonis Martín, Virginia
Martínez-Baz, Iván
William, Naoma
Vilcu, Ana-Maria
Mazagatos, Clara
Domegan, Lisa
de Lusignan, Simon
Meijer, Adam
Machado, Ausenda
Brytting, Mia
Casado, Itziar
Murray, Josephine-L K.
Belhillil, Sylvie
Larrauri, Amparo
O’Donnell, Joan
Tsang, Ruby
de Lange, Marit
Rodrigues, Ana Paula
Riess, Maximilian
Castilla, Jesús
Hamilton, Mark
Falchi, Alessandra
Pozo, Francisco
Dunford, Linda
Cogdale, Jade
Jansen, Tessa
Guiomar, Raquel
Enkirch, Theresa
Burgui, Cristina
Sigerson, Debbie
Blanchon, Thierry
Martínez Ochoa, Eva María
Connell, Jeff
Ellis, Joanna
van Gageldonk-Lafeber, Rianne
Kislaya, Irina
Rose, Angela MC
Valenciano, Marta
Andrews, Nick
Lopez Bernal, Jamie
Whitaker, Heather
Guerrisi, Caroline
Launay, Titouan
Masse, Shirley
van der Werf, Sylvie
Enouf, Vincent
Cuddihy, John
McKenna, Adele
Joyce, Michael
de Gascun, Cillian
Moran, Joanne
Miqueleiz, Ana
Navascués, Ana
Trobajo-Sanmartín, Camino
Ezpeleta, Carmen
Moreno, Paula López
Gorricho, Javier
Ardanaz, Eva
Baigorria, Fernando
Barricarte, Aurelio
de la Cruz, Enrique
Egüés, Nerea
García Cenoz, Manuel
Guevara, Marcela
Moreno-Iribas, Conchi
Sayón, Carmen
Gomez, Verónica
Nunes, Baltazar
Roquete, Rita
Silva, Adriana
Melo, Aryse
Costa, Inês
Verdasca, Nuno
Conde, Patrícia
Marques, Diogo FP
Molesworth, Anna
Quinn, Leanne
Leyton, Miranda
Campbell, Selin
Thoulass, Janine
McMenamin, Jim
Mateo, Ana Martínez
Basile, Luca
Castrillejo, Daniel
Quiñones Rubio, Carmen
Delgado-Sanz, Concepción
Oliva., Jesús
author_sort Kissling, Esther
collection PubMed
description We measured COVID-19 vaccine effectiveness (VE) against symptomatic SARS-CoV-2 infection at primary care/outpatient level among adults ≥ 65 years old using a multicentre test-negative design in eight European countries. We included 592 SARS-CoV-2 cases and 4,372 test-negative controls in the main analysis. The VE was 62% (95% CI: 45–74) for one dose only and 89% (95% CI: 79–94) for complete vaccination. COVID-19 vaccines provide good protection against COVID-19 presentation at primary care/outpatient level, particularly among fully vaccinated individuals.
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spelling pubmed-82997442021-08-02 Vaccine effectiveness against symptomatic SARS-CoV-2 infection in adults aged 65 years and older in primary care: I-MOVE-COVID-19 project, Europe, December 2020 to May 2021 Kissling, Esther Hooiveld, Mariette Sandonis Martín, Virginia Martínez-Baz, Iván William, Naoma Vilcu, Ana-Maria Mazagatos, Clara Domegan, Lisa de Lusignan, Simon Meijer, Adam Machado, Ausenda Brytting, Mia Casado, Itziar Murray, Josephine-L K. Belhillil, Sylvie Larrauri, Amparo O’Donnell, Joan Tsang, Ruby de Lange, Marit Rodrigues, Ana Paula Riess, Maximilian Castilla, Jesús Hamilton, Mark Falchi, Alessandra Pozo, Francisco Dunford, Linda Cogdale, Jade Jansen, Tessa Guiomar, Raquel Enkirch, Theresa Burgui, Cristina Sigerson, Debbie Blanchon, Thierry Martínez Ochoa, Eva María Connell, Jeff Ellis, Joanna van Gageldonk-Lafeber, Rianne Kislaya, Irina Rose, Angela MC Valenciano, Marta Andrews, Nick Lopez Bernal, Jamie Whitaker, Heather Guerrisi, Caroline Launay, Titouan Masse, Shirley van der Werf, Sylvie Enouf, Vincent Cuddihy, John McKenna, Adele Joyce, Michael de Gascun, Cillian Moran, Joanne Miqueleiz, Ana Navascués, Ana Trobajo-Sanmartín, Camino Ezpeleta, Carmen Moreno, Paula López Gorricho, Javier Ardanaz, Eva Baigorria, Fernando Barricarte, Aurelio de la Cruz, Enrique Egüés, Nerea García Cenoz, Manuel Guevara, Marcela Moreno-Iribas, Conchi Sayón, Carmen Gomez, Verónica Nunes, Baltazar Roquete, Rita Silva, Adriana Melo, Aryse Costa, Inês Verdasca, Nuno Conde, Patrícia Marques, Diogo FP Molesworth, Anna Quinn, Leanne Leyton, Miranda Campbell, Selin Thoulass, Janine McMenamin, Jim Mateo, Ana Martínez Basile, Luca Castrillejo, Daniel Quiñones Rubio, Carmen Delgado-Sanz, Concepción Oliva., Jesús Euro Surveill Rapid Communication We measured COVID-19 vaccine effectiveness (VE) against symptomatic SARS-CoV-2 infection at primary care/outpatient level among adults ≥ 65 years old using a multicentre test-negative design in eight European countries. We included 592 SARS-CoV-2 cases and 4,372 test-negative controls in the main analysis. The VE was 62% (95% CI: 45–74) for one dose only and 89% (95% CI: 79–94) for complete vaccination. COVID-19 vaccines provide good protection against COVID-19 presentation at primary care/outpatient level, particularly among fully vaccinated individuals. European Centre for Disease Prevention and Control (ECDC) 2021-07-22 /pmc/articles/PMC8299744/ /pubmed/34296676 http://dx.doi.org/10.2807/1560-7917.ES.2021.26.29.2100670 Text en This article is copyright of the authors or their affiliated institutions, 2021. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution (CC BY 4.0) Licence. You may share and adapt the material, but must give appropriate credit to the source, provide a link to the licence, and indicate if changes were made.
spellingShingle Rapid Communication
Kissling, Esther
Hooiveld, Mariette
Sandonis Martín, Virginia
Martínez-Baz, Iván
William, Naoma
Vilcu, Ana-Maria
Mazagatos, Clara
Domegan, Lisa
de Lusignan, Simon
Meijer, Adam
Machado, Ausenda
Brytting, Mia
Casado, Itziar
Murray, Josephine-L K.
Belhillil, Sylvie
Larrauri, Amparo
O’Donnell, Joan
Tsang, Ruby
de Lange, Marit
Rodrigues, Ana Paula
Riess, Maximilian
Castilla, Jesús
Hamilton, Mark
Falchi, Alessandra
Pozo, Francisco
Dunford, Linda
Cogdale, Jade
Jansen, Tessa
Guiomar, Raquel
Enkirch, Theresa
Burgui, Cristina
Sigerson, Debbie
Blanchon, Thierry
Martínez Ochoa, Eva María
Connell, Jeff
Ellis, Joanna
van Gageldonk-Lafeber, Rianne
Kislaya, Irina
Rose, Angela MC
Valenciano, Marta
Andrews, Nick
Lopez Bernal, Jamie
Whitaker, Heather
Guerrisi, Caroline
Launay, Titouan
Masse, Shirley
van der Werf, Sylvie
Enouf, Vincent
Cuddihy, John
McKenna, Adele
Joyce, Michael
de Gascun, Cillian
Moran, Joanne
Miqueleiz, Ana
Navascués, Ana
Trobajo-Sanmartín, Camino
Ezpeleta, Carmen
Moreno, Paula López
Gorricho, Javier
Ardanaz, Eva
Baigorria, Fernando
Barricarte, Aurelio
de la Cruz, Enrique
Egüés, Nerea
García Cenoz, Manuel
Guevara, Marcela
Moreno-Iribas, Conchi
Sayón, Carmen
Gomez, Verónica
Nunes, Baltazar
Roquete, Rita
Silva, Adriana
Melo, Aryse
Costa, Inês
Verdasca, Nuno
Conde, Patrícia
Marques, Diogo FP
Molesworth, Anna
Quinn, Leanne
Leyton, Miranda
Campbell, Selin
Thoulass, Janine
McMenamin, Jim
Mateo, Ana Martínez
Basile, Luca
Castrillejo, Daniel
Quiñones Rubio, Carmen
Delgado-Sanz, Concepción
Oliva., Jesús
Vaccine effectiveness against symptomatic SARS-CoV-2 infection in adults aged 65 years and older in primary care: I-MOVE-COVID-19 project, Europe, December 2020 to May 2021
title Vaccine effectiveness against symptomatic SARS-CoV-2 infection in adults aged 65 years and older in primary care: I-MOVE-COVID-19 project, Europe, December 2020 to May 2021
title_full Vaccine effectiveness against symptomatic SARS-CoV-2 infection in adults aged 65 years and older in primary care: I-MOVE-COVID-19 project, Europe, December 2020 to May 2021
title_fullStr Vaccine effectiveness against symptomatic SARS-CoV-2 infection in adults aged 65 years and older in primary care: I-MOVE-COVID-19 project, Europe, December 2020 to May 2021
title_full_unstemmed Vaccine effectiveness against symptomatic SARS-CoV-2 infection in adults aged 65 years and older in primary care: I-MOVE-COVID-19 project, Europe, December 2020 to May 2021
title_short Vaccine effectiveness against symptomatic SARS-CoV-2 infection in adults aged 65 years and older in primary care: I-MOVE-COVID-19 project, Europe, December 2020 to May 2021
title_sort vaccine effectiveness against symptomatic sars-cov-2 infection in adults aged 65 years and older in primary care: i-move-covid-19 project, europe, december 2020 to may 2021
topic Rapid Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8299744/
https://www.ncbi.nlm.nih.gov/pubmed/34296676
http://dx.doi.org/10.2807/1560-7917.ES.2021.26.29.2100670
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AT marquesdiogofp vaccineeffectivenessagainstsymptomaticsarscov2infectioninadultsaged65yearsandolderinprimarycareimovecovid19projecteuropedecember2020tomay2021
AT molesworthanna vaccineeffectivenessagainstsymptomaticsarscov2infectioninadultsaged65yearsandolderinprimarycareimovecovid19projecteuropedecember2020tomay2021
AT quinnleanne vaccineeffectivenessagainstsymptomaticsarscov2infectioninadultsaged65yearsandolderinprimarycareimovecovid19projecteuropedecember2020tomay2021
AT leytonmiranda vaccineeffectivenessagainstsymptomaticsarscov2infectioninadultsaged65yearsandolderinprimarycareimovecovid19projecteuropedecember2020tomay2021
AT campbellselin vaccineeffectivenessagainstsymptomaticsarscov2infectioninadultsaged65yearsandolderinprimarycareimovecovid19projecteuropedecember2020tomay2021
AT thoulassjanine vaccineeffectivenessagainstsymptomaticsarscov2infectioninadultsaged65yearsandolderinprimarycareimovecovid19projecteuropedecember2020tomay2021
AT mcmenaminjim vaccineeffectivenessagainstsymptomaticsarscov2infectioninadultsaged65yearsandolderinprimarycareimovecovid19projecteuropedecember2020tomay2021
AT mateoanamartinez vaccineeffectivenessagainstsymptomaticsarscov2infectioninadultsaged65yearsandolderinprimarycareimovecovid19projecteuropedecember2020tomay2021
AT basileluca vaccineeffectivenessagainstsymptomaticsarscov2infectioninadultsaged65yearsandolderinprimarycareimovecovid19projecteuropedecember2020tomay2021
AT castrillejodaniel vaccineeffectivenessagainstsymptomaticsarscov2infectioninadultsaged65yearsandolderinprimarycareimovecovid19projecteuropedecember2020tomay2021
AT quinonesrubiocarmen vaccineeffectivenessagainstsymptomaticsarscov2infectioninadultsaged65yearsandolderinprimarycareimovecovid19projecteuropedecember2020tomay2021
AT delgadosanzconcepcion vaccineeffectivenessagainstsymptomaticsarscov2infectioninadultsaged65yearsandolderinprimarycareimovecovid19projecteuropedecember2020tomay2021
AT olivajesus vaccineeffectivenessagainstsymptomaticsarscov2infectioninadultsaged65yearsandolderinprimarycareimovecovid19projecteuropedecember2020tomay2021