Cargando…

Systems-level biomarkers identification and drug repositioning in colorectal cancer

Colorectal cancer (CRC) is the most commonly diagnosed fatal cancer in both women and men worldwide. CRC ranked second in mortality and third in incidence in 2020. It is difficult to diagnose CRC at an early stage as there are no clinical symptoms. Despite advances in molecular biology, only a limit...

Descripción completa

Detalles Bibliográficos
Autores principales:	Beklen, Hande, Yildirim, Esra, Kori, Medi, Turanli, Beste, Arga, Kazim Yalcin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Baishideng Publishing Group Inc 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8299930/ https://www.ncbi.nlm.nih.gov/pubmed/34322194 http://dx.doi.org/10.4251/wjgo.v13.i7.638

Ejemplares similares

Drug repositioning via host-pathogen protein-protein interactions for the treatment of cervical cancer
por: Kori, Medi, et al.
Publicado: (2023)

Drug Repositioning for P-Glycoprotein Mediated Co-Expression Networks in Colorectal Cancer
por: Beklen, Hande, et al.
Publicado: (2020)

Repositioning of Anti-Inflammatory Drugs for the Treatment of Cervical Cancer Sub-Types
por: Kori, Medi, et al.
Publicado: (2022)

Differential Interactome Based Drug Repositioning Unraveled Abacavir, Exemestane, Nortriptyline Hydrochloride, and Tolcapone as Potential Therapeutics for Colorectal Cancers
por: Beklen, Hande, et al.
Publicado: (2021)

Pan-cancer mapping of differential protein-protein interactions
por: Gulfidan, Gizem, et al.
Publicado: (2020)

Current State of “Omics” Biomarkers in Pancreatic Cancer
por: Turanli, Beste, et al.
Publicado: (2021)

Potential biomarkers and therapeutic targets in cervical cancer: Insights from the meta-analysis of transcriptomics data within network biomedicine perspective
por: Kori, Medi, et al.
Publicado: (2018)

Discovery of therapeutic agents for prostate cancer using genome-scale metabolic modeling and drug repositioning
por: Turanli, Beste, et al.
Publicado: (2019)

Drug Repositioning for Effective Prostate Cancer Treatment
por: Turanli, Beste, et al.
Publicado: (2018)

Identification of Prognostic Biomarker Signatures and Candidate Drugs in Colorectal Cancer: Insights from Systems Biology Analysis
por: Rahman, Md. Rezanur, et al.
Publicado: (2019)

Integrative transcriptomics analysis of lung epithelial cells and identification of repurposable drug candidates for COVID-19
por: Islam, Tania, et al.
Publicado: (2020)

A Pan-Cancer Atlas of Differentially Interacting Hallmarks of Cancer Proteins
por: Kori, Medi, et al.
Publicado: (2022)

Multi-Omic Data Interpretation to Repurpose Subtype Specific Drug Candidates for Breast Cancer
por: Turanli, Beste, et al.
Publicado: (2019)

Differential co-expression analysis reveals a novel prognostic gene module in ovarian cancer
por: Gov, Esra, et al.
Publicado: (2017)

Higher proteotoxic stress rather than mitochondrial damage is involved in higher neurotoxicity of bortezomib compared to carfilzomib
por: Jannuzzi, Ayse Tarbin, et al.
Publicado: (2020)

Bioinformatics Prediction and Machine Learning on Gene Expression Data Identifies Novel Gene Candidates in Gastric Cancer
por: Kori, Medi, et al.
Publicado: (2022)

The role of protein interaction networks in systems biomedicine
por: Sevimoglu, Tuba, et al.
Publicado: (2014)

Omics-Driven Biomarkers of Psoriasis: Recent Insights, Current Challenges, and Future Prospects
por: Aydin, Busra, et al.
Publicado: (2020)

Differential Interactome Proposes Subtype-Specific Biomarkers and Potential Therapeutics in Renal Cell Carcinomas
por: Caliskan, Aysegul, et al.
Publicado: (2021)

Comprehensive Analysis of RNA-Seq Gene Expression Profiling of Brain Transcriptomes Reveals Novel Genes, Regulators, and Pathways in Autism Spectrum Disorder
por: Rahman, Md Rezanur, et al.
Publicado: (2020)

Co-expression Network Analysis Elucidated a Core Module in Association With Prognosis of Non-functioning Non-invasive Human Pituitary Adenoma
por: Aydin, Busra, et al.
Publicado: (2019)

P345: IN SILICO DRUG REPURPOSING STUDY AND MOLECULAR SIGNATURE IDENTIFICATION ON ADULT ACUTE LYMPHOBLASTIC LEUKEMIA
por: Kiraz Durmaz, Yagmur, et al.
Publicado: (2023)

A system based network approach to ethanol tolerance in Saccharomyces cerevisiae
por: Kasavi, Ceyda, et al.
Publicado: (2014)

Editorial: Omics integration and network medicine to decipher human complex diseases
por: Zanfardino, Mario, et al.
Publicado: (2023)

Recent Developments in Cancer Systems Biology: Lessons Learned and Future Directions
por: Arga, Kazim Y., et al.
Publicado: (2021)

Repositioning Drugs for Psychiatry
por: Akhondzadeh, Shahin
Publicado: (2020)

Reposition of the anti-inflammatory drug diacerein in an in-vivo colorectal cancer model
por: Abdel-Latif, Raghda T., et al.
Publicado: (2022)

Repositioned Drugs for Chagas Disease Unveiled via Structure-Based Drug Repositioning
por: Adasme, Melissa F., et al.
Publicado: (2020)

Drug repositioning in drug discovery of T2DM and repositioning potential of antidiabetic agents
por: Zhu, Sha, et al.
Publicado: (2022)

Draft Genome Sequence of Exopolysaccharide-Producing Thermophilic Bacterium Brevibacillus thermoruber Strain 423
por: Yasar Yildiz, Songul, et al.
Publicado: (2013)

Repositioning of Anthelmintic Drugs for the Treatment of Cancers of the Digestive System
por: Laudisi, Federica, et al.
Publicado: (2020)

Transcriptomic profile of Pea3 family members reveal regulatory codes for axon outgrowth and neuronal connection specificity
por: Kandemir, Başak, et al.
Publicado: (2020)

Drug repositioning for personalized medicine
por: Li, Yvonne Y, et al.
Publicado: (2012)

Network mirroring for drug repositioning
por: Park, Sunghong, et al.
Publicado: (2017)

Drug Repositioning for COVID-19
por: Benavides-Cordoba, Vicente
Publicado: (2020)

GREP: genome for REPositioning drugs
por: Sakaue, Saori, et al.
Publicado: (2019)

Transcriptome-Guided Drug Repositioning
por: Arakelyan, Arsen, et al.
Publicado: (2019)

Drug Repositioning in Friedreich Ataxia
por: Rufini, Alessandra, et al.
Publicado: (2022)

Molecular interaction networks and drug development: Novel approach to drug target identification and drug repositioning
por: Loscalzo, Joseph
Publicado: (2022)

Drug repositioning or target repositioning: A structural perspective of drug-target-indication relationship for available repurposed drugs
por: Parisi, Daniele, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_oab96fevijl42ler9ug8brno9j