Auto-Antibody Production During Experimental Atherosclerosis in ApoE(-/-) Mice

Current models stipulate that B cells and antibodies function during atherosclerosis in two distinct ways based on antibody isotype, where IgM is protective and IgG is inflammatory. To examine this model, we generated ApoE(-/-) Aid(-/-) mice, which are unable to produce IgG antibodies due to the abs...

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Detalles Bibliográficos
Autores principales: Hutchinson, Mark A., Park, Han-Sol, Zanotti, Kimberly J., Alvarez-Gonzalez, Juan, Zhang, Jing, Zhang, Li, Telljohann, Richard, Wang, Mingyi, Lakatta, Edward G., Gearhart, Patricia J., Maul, Robert W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8299997/
https://www.ncbi.nlm.nih.gov/pubmed/34305930
http://dx.doi.org/10.3389/fimmu.2021.695220

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