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IRF1 governs the differential interferon-stimulated gene responses in human monocytes and macrophages by regulating chromatin accessibility

Myeloid lineage cells use TLRs to recognize and respond to diverse microbial ligands. Although unique transcription factors dictate the outcome of specific TLR signaling, whether lineage-specific differences exist to further modulate the quality of TLR-induced inflammation remains unclear. Comprehen...

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Detalles Bibliográficos
Autores principales:	Song, Ran, Gao, Yajing, Dozmorov, Igor, Malladi, Venkat, Saha, Irene, McDaniel, Margaret M., Parameswaran, Sreeja, Liang, Chaoying, Arana, Carlos, Zhang, Bo, Wakeland, Benjamin, Zhou, Jinchun, Weirauch, Matthew T., Kottyan, Leah C., Wakeland, Edward K., Pasare, Chandrashekhar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8300000/ https://www.ncbi.nlm.nih.gov/pubmed/33761354 http://dx.doi.org/10.1016/j.celrep.2021.108891

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