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Activated Blood Coagulation Factor X (FXa) Contributes to the Development of Traumatic PVR Through Promoting RPE Epithelial-Mesenchymal Transition

PURPOSE: Uncontrolled coagulation reactions contribute to pathological fibroproliferation in several organs, and yet their role in proliferative vitreoretinopathy (PVR) remains to be elucidated. In this study, we evaluated the profibrotic effects of FXa in RPE cells and in a mouse model of PVR. METH...

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Detalles Bibliográficos
Autores principales:	Han, Han, Zhao, Xiao, Liao, Mengyu, Song, Yinting, You, Caiyun, Dong, Xue, Yang, Xueli, Wang, Xiaohong, Huang, Bo, Du, Mei, Yan, Hua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Association for Research in Vision and Ophthalmology 2021
Materias:	Retina
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8300057/ https://www.ncbi.nlm.nih.gov/pubmed/34283209 http://dx.doi.org/10.1167/iovs.62.9.29

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