Cargando…
Antibiotic Prescriptions for Respiratory Tract Viral Infections in the Colombian Population
Antimicrobials are frequently inappropriately prescribed for the management of upper respiratory tract infections (URTIs); therefore, the frequency of antibiotic prescriptions for patients with viral URTIs was assessed in this study. A cross-sectional study, including ambulatory patients diagnosed w...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8300612/ https://www.ncbi.nlm.nih.gov/pubmed/34356785 http://dx.doi.org/10.3390/antibiotics10070864 |
_version_ | 1783726489740509184 |
---|---|
author | Machado-Duque, Manuel E. García, Diego Arturo Emura-Velez, Melissa Hiromi Gaviria-Mendoza, Andrés Giraldo-Giraldo, Claudia Machado-Alba, Jorge E. |
author_facet | Machado-Duque, Manuel E. García, Diego Arturo Emura-Velez, Melissa Hiromi Gaviria-Mendoza, Andrés Giraldo-Giraldo, Claudia Machado-Alba, Jorge E. |
author_sort | Machado-Duque, Manuel E. |
collection | PubMed |
description | Antimicrobials are frequently inappropriately prescribed for the management of upper respiratory tract infections (URTIs); therefore, the frequency of antibiotic prescriptions for patients with viral URTIs was assessed in this study. A cross-sectional study, including ambulatory patients diagnosed with viral URTI, was conducted, and records of antimicrobial prescriptions were obtained. Sociodemographic, clinical (diagnostic), and pharmacological (antimicrobial) variables were assessed. Through multivariate analysis, variables associated with the use of antibiotics for viral infections were identified. A total of 341,182 patients with viral URTIs were identified. The patients, who were from 26 different departments of Colombia, had a mean age of 29.7 ± 23.5 years and a female predominance of 58.7% (n = 200,195). The most frequent viral infections were as follows: acute rhinopharyngitis (common cold) (n = 206,211; 60.4%); unspecified acute tonsillitis (n = 27,432; 8.0%); and acute pharyngitis (n = 26,411; 7.7%). A total of 24.8% of the patients (n = 84,453) received a prescription for antibiotics, predominantly penicillins (n = 61,871; 18.1%) and cephalosporins (n = 10,926; 3.2%). Patients treated in Atlántico, Valle, and Risaralda departments, along with those older than 5 years, were more likely to receive antibiotics for the treatment of viral infections. Antibiotics are frequently prescribed for the management of URTIs, which is considered an inappropriate practice due to a lack of clinical benefits, increased generation of antimicrobial resistance, and a risk of adverse reactions due to the use of medications that patients do not require. Drug utilization studies are a great tool for monitoring how antibiotics are being used and planning interventions to improve their use. |
format | Online Article Text |
id | pubmed-8300612 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-83006122021-07-24 Antibiotic Prescriptions for Respiratory Tract Viral Infections in the Colombian Population Machado-Duque, Manuel E. García, Diego Arturo Emura-Velez, Melissa Hiromi Gaviria-Mendoza, Andrés Giraldo-Giraldo, Claudia Machado-Alba, Jorge E. Antibiotics (Basel) Article Antimicrobials are frequently inappropriately prescribed for the management of upper respiratory tract infections (URTIs); therefore, the frequency of antibiotic prescriptions for patients with viral URTIs was assessed in this study. A cross-sectional study, including ambulatory patients diagnosed with viral URTI, was conducted, and records of antimicrobial prescriptions were obtained. Sociodemographic, clinical (diagnostic), and pharmacological (antimicrobial) variables were assessed. Through multivariate analysis, variables associated with the use of antibiotics for viral infections were identified. A total of 341,182 patients with viral URTIs were identified. The patients, who were from 26 different departments of Colombia, had a mean age of 29.7 ± 23.5 years and a female predominance of 58.7% (n = 200,195). The most frequent viral infections were as follows: acute rhinopharyngitis (common cold) (n = 206,211; 60.4%); unspecified acute tonsillitis (n = 27,432; 8.0%); and acute pharyngitis (n = 26,411; 7.7%). A total of 24.8% of the patients (n = 84,453) received a prescription for antibiotics, predominantly penicillins (n = 61,871; 18.1%) and cephalosporins (n = 10,926; 3.2%). Patients treated in Atlántico, Valle, and Risaralda departments, along with those older than 5 years, were more likely to receive antibiotics for the treatment of viral infections. Antibiotics are frequently prescribed for the management of URTIs, which is considered an inappropriate practice due to a lack of clinical benefits, increased generation of antimicrobial resistance, and a risk of adverse reactions due to the use of medications that patients do not require. Drug utilization studies are a great tool for monitoring how antibiotics are being used and planning interventions to improve their use. MDPI 2021-07-16 /pmc/articles/PMC8300612/ /pubmed/34356785 http://dx.doi.org/10.3390/antibiotics10070864 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Machado-Duque, Manuel E. García, Diego Arturo Emura-Velez, Melissa Hiromi Gaviria-Mendoza, Andrés Giraldo-Giraldo, Claudia Machado-Alba, Jorge E. Antibiotic Prescriptions for Respiratory Tract Viral Infections in the Colombian Population |
title | Antibiotic Prescriptions for Respiratory Tract Viral Infections in the Colombian Population |
title_full | Antibiotic Prescriptions for Respiratory Tract Viral Infections in the Colombian Population |
title_fullStr | Antibiotic Prescriptions for Respiratory Tract Viral Infections in the Colombian Population |
title_full_unstemmed | Antibiotic Prescriptions for Respiratory Tract Viral Infections in the Colombian Population |
title_short | Antibiotic Prescriptions for Respiratory Tract Viral Infections in the Colombian Population |
title_sort | antibiotic prescriptions for respiratory tract viral infections in the colombian population |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8300612/ https://www.ncbi.nlm.nih.gov/pubmed/34356785 http://dx.doi.org/10.3390/antibiotics10070864 |
work_keys_str_mv | AT machadoduquemanuele antibioticprescriptionsforrespiratorytractviralinfectionsinthecolombianpopulation AT garciadiegoarturo antibioticprescriptionsforrespiratorytractviralinfectionsinthecolombianpopulation AT emuravelezmelissahiromi antibioticprescriptionsforrespiratorytractviralinfectionsinthecolombianpopulation AT gaviriamendozaandres antibioticprescriptionsforrespiratorytractviralinfectionsinthecolombianpopulation AT giraldogiraldoclaudia antibioticprescriptionsforrespiratorytractviralinfectionsinthecolombianpopulation AT machadoalbajorgee antibioticprescriptionsforrespiratorytractviralinfectionsinthecolombianpopulation |