Cargando…

Antibiotic Prescriptions for Respiratory Tract Viral Infections in the Colombian Population

Antimicrobials are frequently inappropriately prescribed for the management of upper respiratory tract infections (URTIs); therefore, the frequency of antibiotic prescriptions for patients with viral URTIs was assessed in this study. A cross-sectional study, including ambulatory patients diagnosed w...

Descripción completa

Detalles Bibliográficos
Autores principales: Machado-Duque, Manuel E., García, Diego Arturo, Emura-Velez, Melissa Hiromi, Gaviria-Mendoza, Andrés, Giraldo-Giraldo, Claudia, Machado-Alba, Jorge E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8300612/
https://www.ncbi.nlm.nih.gov/pubmed/34356785
http://dx.doi.org/10.3390/antibiotics10070864
_version_ 1783726489740509184
author Machado-Duque, Manuel E.
García, Diego Arturo
Emura-Velez, Melissa Hiromi
Gaviria-Mendoza, Andrés
Giraldo-Giraldo, Claudia
Machado-Alba, Jorge E.
author_facet Machado-Duque, Manuel E.
García, Diego Arturo
Emura-Velez, Melissa Hiromi
Gaviria-Mendoza, Andrés
Giraldo-Giraldo, Claudia
Machado-Alba, Jorge E.
author_sort Machado-Duque, Manuel E.
collection PubMed
description Antimicrobials are frequently inappropriately prescribed for the management of upper respiratory tract infections (URTIs); therefore, the frequency of antibiotic prescriptions for patients with viral URTIs was assessed in this study. A cross-sectional study, including ambulatory patients diagnosed with viral URTI, was conducted, and records of antimicrobial prescriptions were obtained. Sociodemographic, clinical (diagnostic), and pharmacological (antimicrobial) variables were assessed. Through multivariate analysis, variables associated with the use of antibiotics for viral infections were identified. A total of 341,182 patients with viral URTIs were identified. The patients, who were from 26 different departments of Colombia, had a mean age of 29.7 ± 23.5 years and a female predominance of 58.7% (n = 200,195). The most frequent viral infections were as follows: acute rhinopharyngitis (common cold) (n = 206,211; 60.4%); unspecified acute tonsillitis (n = 27,432; 8.0%); and acute pharyngitis (n = 26,411; 7.7%). A total of 24.8% of the patients (n = 84,453) received a prescription for antibiotics, predominantly penicillins (n = 61,871; 18.1%) and cephalosporins (n = 10,926; 3.2%). Patients treated in Atlántico, Valle, and Risaralda departments, along with those older than 5 years, were more likely to receive antibiotics for the treatment of viral infections. Antibiotics are frequently prescribed for the management of URTIs, which is considered an inappropriate practice due to a lack of clinical benefits, increased generation of antimicrobial resistance, and a risk of adverse reactions due to the use of medications that patients do not require. Drug utilization studies are a great tool for monitoring how antibiotics are being used and planning interventions to improve their use.
format Online
Article
Text
id pubmed-8300612
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-83006122021-07-24 Antibiotic Prescriptions for Respiratory Tract Viral Infections in the Colombian Population Machado-Duque, Manuel E. García, Diego Arturo Emura-Velez, Melissa Hiromi Gaviria-Mendoza, Andrés Giraldo-Giraldo, Claudia Machado-Alba, Jorge E. Antibiotics (Basel) Article Antimicrobials are frequently inappropriately prescribed for the management of upper respiratory tract infections (URTIs); therefore, the frequency of antibiotic prescriptions for patients with viral URTIs was assessed in this study. A cross-sectional study, including ambulatory patients diagnosed with viral URTI, was conducted, and records of antimicrobial prescriptions were obtained. Sociodemographic, clinical (diagnostic), and pharmacological (antimicrobial) variables were assessed. Through multivariate analysis, variables associated with the use of antibiotics for viral infections were identified. A total of 341,182 patients with viral URTIs were identified. The patients, who were from 26 different departments of Colombia, had a mean age of 29.7 ± 23.5 years and a female predominance of 58.7% (n = 200,195). The most frequent viral infections were as follows: acute rhinopharyngitis (common cold) (n = 206,211; 60.4%); unspecified acute tonsillitis (n = 27,432; 8.0%); and acute pharyngitis (n = 26,411; 7.7%). A total of 24.8% of the patients (n = 84,453) received a prescription for antibiotics, predominantly penicillins (n = 61,871; 18.1%) and cephalosporins (n = 10,926; 3.2%). Patients treated in Atlántico, Valle, and Risaralda departments, along with those older than 5 years, were more likely to receive antibiotics for the treatment of viral infections. Antibiotics are frequently prescribed for the management of URTIs, which is considered an inappropriate practice due to a lack of clinical benefits, increased generation of antimicrobial resistance, and a risk of adverse reactions due to the use of medications that patients do not require. Drug utilization studies are a great tool for monitoring how antibiotics are being used and planning interventions to improve their use. MDPI 2021-07-16 /pmc/articles/PMC8300612/ /pubmed/34356785 http://dx.doi.org/10.3390/antibiotics10070864 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Machado-Duque, Manuel E.
García, Diego Arturo
Emura-Velez, Melissa Hiromi
Gaviria-Mendoza, Andrés
Giraldo-Giraldo, Claudia
Machado-Alba, Jorge E.
Antibiotic Prescriptions for Respiratory Tract Viral Infections in the Colombian Population
title Antibiotic Prescriptions for Respiratory Tract Viral Infections in the Colombian Population
title_full Antibiotic Prescriptions for Respiratory Tract Viral Infections in the Colombian Population
title_fullStr Antibiotic Prescriptions for Respiratory Tract Viral Infections in the Colombian Population
title_full_unstemmed Antibiotic Prescriptions for Respiratory Tract Viral Infections in the Colombian Population
title_short Antibiotic Prescriptions for Respiratory Tract Viral Infections in the Colombian Population
title_sort antibiotic prescriptions for respiratory tract viral infections in the colombian population
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8300612/
https://www.ncbi.nlm.nih.gov/pubmed/34356785
http://dx.doi.org/10.3390/antibiotics10070864
work_keys_str_mv AT machadoduquemanuele antibioticprescriptionsforrespiratorytractviralinfectionsinthecolombianpopulation
AT garciadiegoarturo antibioticprescriptionsforrespiratorytractviralinfectionsinthecolombianpopulation
AT emuravelezmelissahiromi antibioticprescriptionsforrespiratorytractviralinfectionsinthecolombianpopulation
AT gaviriamendozaandres antibioticprescriptionsforrespiratorytractviralinfectionsinthecolombianpopulation
AT giraldogiraldoclaudia antibioticprescriptionsforrespiratorytractviralinfectionsinthecolombianpopulation
AT machadoalbajorgee antibioticprescriptionsforrespiratorytractviralinfectionsinthecolombianpopulation