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Elexacaftor–Tezacaftor–Ivacaftor Therapy for Cystic Fibrosis Patients with The F508del/Unknown Genotype
The new CFTR modulator combination, elexacaftor/tezacaftor/ivacaftor (Trikafta) was approved by the FDA in October 2019 for treatment of Cystic Fibrosis in patients 6 years of age or older who have at least one F508del mutation in one allele and a minimal-function or another F508del mutation in the...
Autores principales: | Comegna, Marika, Terlizzi, Vito, Salvatore, Donatello, Colangelo, Carmela, Di Lullo, Antonella Miriam, Zollo, Immacolata, Taccetti, Giovanni, Castaldo, Giuseppe, Amato, Felice |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8300667/ https://www.ncbi.nlm.nih.gov/pubmed/34356748 http://dx.doi.org/10.3390/antibiotics10070828 |
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