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Influence of Alternative Lifestyles on Antibiotic Use during Pregnancy, Lactation and in Children

Alternative lifestyles are likely to be associated with distinct usage of specific medicinal products. Our goal was to find out whether the intake of antibiotics during pregnancy and by children differs according to whether the mothers have alternative or conventional lifestyles. Therefore, we inves...

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Autores principales: Eras, Pien, Simões-Wüst, Ana Paula, Thijs, Carel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8300802/
https://www.ncbi.nlm.nih.gov/pubmed/34356758
http://dx.doi.org/10.3390/antibiotics10070837
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author Eras, Pien
Simões-Wüst, Ana Paula
Thijs, Carel
author_facet Eras, Pien
Simões-Wüst, Ana Paula
Thijs, Carel
author_sort Eras, Pien
collection PubMed
description Alternative lifestyles are likely to be associated with distinct usage of specific medicinal products. Our goal was to find out whether the intake of antibiotics during pregnancy and by children differs according to whether the mothers have alternative or conventional lifestyles. Therefore, we investigated the use of antibiotics by pregnant women and by children up to 11 years of age participating in the KOALA Birth Cohort Study. This cohort comprises two recruitment groups of mother–infant pairs, one with alternative lifestyles (selected via organic food shops, anthroposophic clinicians and midwives, anthroposophic under-five clinics, Rudolf Steiner schools and relevant magazines, n = 491) the other with conventional lifestyles (no selection based on lifestyle, n = 2343). Mothers in the alternative lifestyle group more frequently adhered to specific living rules and identified themselves with anthroposophy more than mothers in the conventional lifestyle group. The results revealed significant differences in antibiotic use during pregnancy and in children from 3 months to 10 years of age between the two groups. The rate of antibiotic use in children was consistently lower in the alternative lifestyle group than in the conventional lifestyle group. Antibiotic use in pregnancy was higher in low educated women, and maternal antibiotic use during lactation was higher after an instrumented delivery in hospital. Antibiotic use in the infant was higher when they had older sibs or were born in hospital, and lower in those who had been longer breastfed. After adjustment for these factors, the differences in antibiotic use between the alternative and conventional groups remained. The results suggest that an alternative lifestyle is associated with cautious antibiotic use during pregnancy, lactation and in children.
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spelling pubmed-83008022021-07-24 Influence of Alternative Lifestyles on Antibiotic Use during Pregnancy, Lactation and in Children Eras, Pien Simões-Wüst, Ana Paula Thijs, Carel Antibiotics (Basel) Article Alternative lifestyles are likely to be associated with distinct usage of specific medicinal products. Our goal was to find out whether the intake of antibiotics during pregnancy and by children differs according to whether the mothers have alternative or conventional lifestyles. Therefore, we investigated the use of antibiotics by pregnant women and by children up to 11 years of age participating in the KOALA Birth Cohort Study. This cohort comprises two recruitment groups of mother–infant pairs, one with alternative lifestyles (selected via organic food shops, anthroposophic clinicians and midwives, anthroposophic under-five clinics, Rudolf Steiner schools and relevant magazines, n = 491) the other with conventional lifestyles (no selection based on lifestyle, n = 2343). Mothers in the alternative lifestyle group more frequently adhered to specific living rules and identified themselves with anthroposophy more than mothers in the conventional lifestyle group. The results revealed significant differences in antibiotic use during pregnancy and in children from 3 months to 10 years of age between the two groups. The rate of antibiotic use in children was consistently lower in the alternative lifestyle group than in the conventional lifestyle group. Antibiotic use in pregnancy was higher in low educated women, and maternal antibiotic use during lactation was higher after an instrumented delivery in hospital. Antibiotic use in the infant was higher when they had older sibs or were born in hospital, and lower in those who had been longer breastfed. After adjustment for these factors, the differences in antibiotic use between the alternative and conventional groups remained. The results suggest that an alternative lifestyle is associated with cautious antibiotic use during pregnancy, lactation and in children. MDPI 2021-07-09 /pmc/articles/PMC8300802/ /pubmed/34356758 http://dx.doi.org/10.3390/antibiotics10070837 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Eras, Pien
Simões-Wüst, Ana Paula
Thijs, Carel
Influence of Alternative Lifestyles on Antibiotic Use during Pregnancy, Lactation and in Children
title Influence of Alternative Lifestyles on Antibiotic Use during Pregnancy, Lactation and in Children
title_full Influence of Alternative Lifestyles on Antibiotic Use during Pregnancy, Lactation and in Children
title_fullStr Influence of Alternative Lifestyles on Antibiotic Use during Pregnancy, Lactation and in Children
title_full_unstemmed Influence of Alternative Lifestyles on Antibiotic Use during Pregnancy, Lactation and in Children
title_short Influence of Alternative Lifestyles on Antibiotic Use during Pregnancy, Lactation and in Children
title_sort influence of alternative lifestyles on antibiotic use during pregnancy, lactation and in children
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8300802/
https://www.ncbi.nlm.nih.gov/pubmed/34356758
http://dx.doi.org/10.3390/antibiotics10070837
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