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Na/H Exchange Regulatory Factor 1 Deficient Mice Show Evidence of Oxidative Stress and Altered Cisplatin Pharmacokinetics

(1) Background: One third of patients who receive cisplatin develop an acute kidney injury. We previously demonstrated the Na/H Exchange Regulatory Factor 1 (NHERF1) loss resulted in increased kidney enzyme activity of the pentose phosphate pathway and was associated with more severe cisplatin nephr...

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Detalles Bibliográficos
Autores principales: Bushau-Sprinkle, Adrienne M., Barati, Michelle T., Zheng, Yuxuan, Watson, Walter H., Gagnon, Kenneth B., Khundmiri, Syed Jalal, Kitterman, Kathleen T., Clark, Barbara J., Siskind, Leah J., Doll, Mark A., Brier, Michael E., Coventry, Susan, Lederer, Eleanor D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8300832/
https://www.ncbi.nlm.nih.gov/pubmed/34203453
http://dx.doi.org/10.3390/antiox10071036