Cargando…
Tanshinone IIA Stimulates Cystathionine γ-Lyase Expression and Protects Endothelial Cells from Oxidative Injury
Tanshinone IIA (Tan IIA), an active ingredient of Danshen, is a well-used drug to treat cardiovascular diseases. Currently, the mechanisms involved remain poorly understood. Given that many actions of Tan IIA could be similarly achieved by hydrogen sulfide (H(2)S), we speculated that Tan IIA might w...
Autores principales: | Yan, Qiaojing, Mao, Zhimin, Hong, Jingru, Gao, Kun, Niimi, Manabu, Mitsui, Takahiko, Yao, Jian |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8300834/ https://www.ncbi.nlm.nih.gov/pubmed/34201701 http://dx.doi.org/10.3390/antiox10071007 |
Ejemplares similares
-
Downregulation of cystathionine β‐synthase and cystathionine γ‐lyase expression stimulates inflammation in kidney ischemia–reperfusion injury
por: Wang, Pengqi, et al.
Publicado: (2014) -
3-Mercaptopyruvate Sulfurtransferase, Not Cystathionine β-Synthase Nor Cystathionine γ-Lyase, Mediates Hypoxia-Induced Migration of Vascular Endothelial Cells
por: Tao, Beibei, et al.
Publicado: (2017) -
Transcriptional Regulation of Cystathionine-γ-Lyase in Endothelial Cells by NADPH Oxidase 4-Dependent Signaling
por: Mistry, Rajesh K., et al.
Publicado: (2016) -
Selectivity of commonly used pharmacological inhibitors for cystathionine β synthase (CBS) and cystathionine γ lyase (CSE)
por: Asimakopoulou, Antonia, et al.
Publicado: (2013) -
A cardioprotective insight of the cystathionine γ-lyase/hydrogen sulfide pathway
por: Huang, Steve, et al.
Publicado: (2015)