Quercetin Alleviates the Accumulation of Superoxide in Sodium Iodate-Induced Retinal Autophagy by Regulating Mitochondrial Reactive Oxygen Species Homeostasis through Enhanced Deacetyl-SOD2 via the Nrf2-PGC-1α-Sirt1 Pathway

Oxidative damage of retinal pigment epithelium (RPE) cells plays an important role in the pathogenesis of blindness-related diseases, such as age-related macular degeneration (AMD). Quercetin, a bioactive flavonoid compound, has been shown to have a protective effect against oxidative stress-induced...

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Detalles Bibliográficos
Autores principales: Hsu, Min-Yen, Hsiao, Yai-Ping, Lin, Yu-Ta, Chen, Connie, Lee, Chee-Ming, Liao, Wen-Chieh, Tsou, Shang-Chun, Lin, Hui-Wen, Chang, Yuan-Yen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8301007/
https://www.ncbi.nlm.nih.gov/pubmed/34356358
http://dx.doi.org/10.3390/antiox10071125

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