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Phenolic Extracts from Extra Virgin Olive Oils Inhibit Dipeptidyl Peptidase IV Activity: In Vitro, Cellular, and In Silico Molecular Modeling Investigations
Two extra virgin olive oil (EVOO) phenolic extracts (BUO and OMN) modulate DPP-IV activity. The in vitro DPP-IV activity assay was performed at the concentrations of 1, 10, 100, 500, and 1000 μg/mL, showing a dose-dependent inhibition by 6.8 ± 1.9, 17.4 ± 6.1, 37.9 ± 2.4, 57.8 ± 2.9, and 81 ± 1.4% f...
Autores principales: | Lammi, Carmen, Bartolomei, Martina, Bollati, Carlotta, Cecchi, Lorenzo, Bellumori, Maria, Sabato, Emanuela, Giulio, Vistoli, Mulinacci, Nadia, Arnoldi, Anna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8301156/ https://www.ncbi.nlm.nih.gov/pubmed/34356366 http://dx.doi.org/10.3390/antiox10071133 |
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