New Benzimidazothiazolone Derivatives as Tyrosinase Inhibitors with Potential Anti-Melanogenesis and Reactive Oxygen Species Scavenging Activities

Thirteen (Z)-2-(substituted benzylidene)benzimidazothiazolone analogs were synthesized and evaluated for their inhibitory activity against mushroom tyrosinase. Among the compounds synthesized, compounds 1–3 showed greater inhibitory activity than kojic acid (IC(50) = 18.27 ± 0.89 μM); IC(50) = 3.70...

Descripción completa

Detalles Bibliográficos
Autores principales: Jung, Hee Jin, Choi, Dong Chan, Noh, Sang Gyun, Choi, Heejeong, Choi, Inkyu, Ryu, Il Young, Chung, Hae Young, Moon, Hyung Ryong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8301170/
https://www.ncbi.nlm.nih.gov/pubmed/34356311
http://dx.doi.org/10.3390/antiox10071078

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8301170/
https://www.ncbi.nlm.nih.gov/pubmed/34356311
http://dx.doi.org/10.3390/antiox10071078

Ejemplares similares