Cargando…

Poly (ADP-Ribose) Polymerase Inhibitor, ABT888, Improved Cisplatin Effect in Human Oral Cell Carcinoma

Cisplatin is one of the chemotherapeutic drugs used for the management of oral carcinoma, in which combined therapies are estimated to exert superior therapeutic efficacy compared with monotherapy. It is known that poly(ADP-ribosyl)ation is implicated in a multiplicity of cellular activities, such a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Paterniti, Irene, Scuderi, Sarah Adriana, Casili, Giovanna, Lanza, Marika, Mare, Marzia, Giuffrida, Raffella, Colarossi, Cristina, Portelli, Marco, Cuzzocrea, Salvatore, Esposito, Emanuela
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8301366/ https://www.ncbi.nlm.nih.gov/pubmed/34356835 http://dx.doi.org/10.3390/biomedicines9070771

Ejemplares similares

Immunomodulatory Effect of Microglia-Released Cytokines in Gliomas
por: Lanza, Marika, et al.
Publicado: (2021)

Evaluation of poly (ADP-ribose) polymerase inhibitor ABT-888 combined with radiotherapy and temozolomide in glioblastoma
por: Barazzuol, Lara, et al.
Publicado: (2013)

Radiosensitization of Pancreatic Cancer Cells In Vitro and In Vivo through Poly (ADP-ribose) Polymerase Inhibition with ABT-888
por: Tuli, Richard, et al.
Publicado: (2014)

Modeling Pharmacodynamic Response to the Poly(ADP-Ribose) Polymerase Inhibitor ABT-888 in Human Peripheral Blood Mononuclear Cells
por: Ji, Jiuping, et al.
Publicado: (2011)

Therapeutic Potential of BAY-117082, a Selective NLRP3 Inflammasome Inhibitor, on Metastatic Evolution in Human Oral Squamous Cell Carcinoma (OSCC)
por: Casili, Giovanna, et al.
Publicado: (2023)

Role of Basic Fibroblast Growth Factor in Cancer: Biological Activity, Targeted Therapies, and Prognostic Value
por: Ardizzone, Alessio, et al.
Publicado: (2023)

TBK1 Inhibitor Exerts Antiproliferative Effect on Glioblastoma Multiforme Cells
por: Scuderi, Sarah A., et al.
Publicado: (2021)

PEA-OXA Mitigates Oxaliplatin-Induced Painful Neuropathy through NF-κB/Nrf-2 Axis
por: Campolo, Michela, et al.
Publicado: (2021)

Beneficial effect of KYP-2047, a propyl-oligopeptidase inhibitor, on oral squamous cell carcinoma
por: Scuderi, Sarah Adriana, et al.
Publicado: (2021)

Protein Kinase Inhibitors as a New Target for Immune System Modulation and Brain Cancer Management
por: Filippone, Alessia, et al.
Publicado: (2022)

Treatment with Luteolin Improves Lipopolysaccharide-Induced Periodontal Diseases in Rats
por: Casili, Giovanna, et al.
Publicado: (2020)

Evaluation of Concurrent Radiation, Temozolomide and ABT-888 Treatment Followed by Maintenance Therapy with Temozolomide and ABT-888 in a Genetically Engineered Glioblastoma Mouse Model
por: Lemasson, Benjamin, et al.
Publicado: (2016)

The Pivotal Role of Protein Phosphatase 2A (PP2A) in Brain Tumors
por: Cucinotta, Laura, et al.
Publicado: (2022)

Effect of a Product Containing Xyloglucan and Pea Protein on a Murine Model of Atopic Dermatitis
por: Campolo, Michela, et al.
Publicado: (2020)

Synergic Therapeutic Potential of PEA-Um Treatment and NAAA Enzyme Silencing In the Management of Neuroinflammation
por: Casili, Giovanna, et al.
Publicado: (2020)

Supplementation with SCFAs Re-Establishes Microbiota Composition and Attenuates Hyperalgesia and Pain in a Mouse Model of NTG-Induced Migraine
por: Lanza, Marika, et al.
Publicado: (2022)

NLRP3 Inflammasome Inhibitor BAY-117082 Reduces Oral Squamous Cell Carcinoma Progression
por: Scuderi, Sarah Adriana, et al.
Publicado: (2021)

The inhibition of mammalian target of rapamycin (mTOR) in improving inflammatory response after traumatic brain injury
por: Campolo, Michela, et al.
Publicado: (2021)

ABT-888 restores sensitivity in temozolomide resistant glioma cells and xenografts
por: Yuan, Alice L., et al.
Publicado: (2018)

Evaluation of ABT-888 in the amelioration of α-synuclein fibril-induced neurodegeneration
por: Hastings, Lyndsay, et al.
Publicado: (2022)

Sodium Propionate Contributes to Tumor Cell Growth Inhibition through PPAR-γ Signaling
por: Filippone, Alessia, et al.
Publicado: (2022)

Effect of a combination of pea protein, grape seed extract and lactic acid in an in vivo model of bacterial vaginosis
por: Lanza, Marika, et al.
Publicado: (2023)

RNA regulation by Poly(ADP-ribose) polymerases
por: Bock, Florian J., et al.
Publicado: (2015)

Mitotic functions of poly(ADP-ribose) polymerases
por: Slade, Dea
Publicado: (2019)

The Antiviral Activities of Poly-ADP-Ribose Polymerases
por: Malgras, Mathilde, et al.
Publicado: (2021)

Efficacy of a Product Containing Xyloglucan and Pea Protein on Intestinal Barrier Function in a Partial Restraint Stress Animal Model
por: Scuderi, Sarah Adriana, et al.
Publicado: (2022)

Overview on Common Genes Involved in the Onset of Glioma and on the Role of Migraine as Risk Factor: Predictive Biomarkers or Therapeutic Targets?
por: Casili, Giovanna, et al.
Publicado: (2022)

KYP-2047, an Inhibitor of Prolyl-Oligopeptidase, Reduces GlioBlastoma Proliferation through Angiogenesis and Apoptosis Modulation
por: Scuderi, Sarah Adriana, et al.
Publicado: (2021)

The PARP inhibitor ABT-888 potentiates darbazine-induced cell death in carcinoids
por: Somnay, Yash, et al.
Publicado: (2016)

Effect of ABT-888 on the apoptosis, motility and invasiveness of BRAFi-resistant melanoma cells
por: Fratangelo, Federica, et al.
Publicado: (2018)

Multiple mechanisms of dimethyl fumarate in amyloid β‐induced neurotoxicity in human neuronal cells
por: Campolo, Michela, et al.
Publicado: (2017)

The Anti-Inflammatory and Antioxidant Effects of Sodium Propionate
por: Filippone, Alessia, et al.
Publicado: (2020)

Dimethyl fumarate alleviates the nitroglycerin (NTG)-induced migraine in mice
por: Casili, Giovanna, et al.
Publicado: (2020)

Evaluating the Protective Properties of a Xyloglucan-Based Nasal Spray in a Mouse Model of Allergic Rhinitis
por: Lanza, Marika, et al.
Publicado: (2021)

Efficacy of a Novel Therapeutic, Based on Natural Ingredients and Probiotics, in a Murine Model of Multiple Food Intolerance and Maldigestion
por: Ardizzone, Alessio, et al.
Publicado: (2022)

Evaluation of the Efficacy of Xyloglucan, Pea Protein and Opuntia ficus-indica Extract in a Preclinical Model of Psoriasis
por: Filippone, Alessia, et al.
Publicado: (2023)

Role of Fibroblast Growth Factors Receptors (FGFRs) in Brain Tumors, Focus on Astrocytoma and Glioblastoma
por: Ardizzone, Alessio, et al.
Publicado: (2020)

Modulation of NLRP3 Inflammasome Attenuated Inflammatory Response Associated to Diarrhea-Predominant Irritable Bowel Syndrome
por: Scuderi, Sarah Adriana, et al.
Publicado: (2020)

The Inhibition of Prolyl Oligopeptidase as New Target to Counteract Chronic Venous Insufficiency: Findings in a Mouse Model
por: Casili, Giovanna, et al.
Publicado: (2020)

Poly(ADP-ribose) polymerase inhibitors in Ewing sarcoma
por: Vormoor, Britta, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_5kcnk87a5vkk9laulmd67819du