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PI3K as Mediator of Apoptosis and Contractile Dysfunction in TGFβ(1)-Stimulated Cardiomyocytes

SIMPLE SUMMARY: TGFβ(1) is a growth factor that plays a major role in the remodeling process of the heart by inducing cardiomyocytes dysfunction and apoptosis, as well as fibrosis, thereby restricting heart function. TGFβ(1) mediates its effect via the TGFβ receptor I (ALK5) and the activation of SM...

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Detalles Bibliográficos
Autores principales:	Brosinsky, Paulin, Bornbaum, Julia, Warga, Björn, Schulz, Lisa, Schlüter, Klaus-Dieter, Ghigo, Alessandra, Hirsch, Emilio, Schulz, Rainer, Euler, Gerhild, Heger, Jacqueline
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8301398/ https://www.ncbi.nlm.nih.gov/pubmed/34356525 http://dx.doi.org/10.3390/biology10070670

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