Cargando…

LncRNAs Associated with Neuronal Development and Oncogenesis Are Deregulated in SOD1-G93A Murine Model of Amyotrophic Lateral Sclerosis

Amyotrophic Lateral Sclerosis (ALS) is a devastating neurodegenerative disease caused in 10% of cases by inherited mutations considered “familial”. An ever-increasing amount of evidence is showing a fundamental role for RNA metabolism in ALS pathogenesis, and long non-coding RNAs (lncRNAs) appear to...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rey, Federica, Marcuzzo, Stefania, Bonanno, Silvia, Bordoni, Matteo, Giallongo, Toniella, Malacarne, Claudia, Cereda, Cristina, Zuccotti, Gian Vincenzo, Carelli, Stephana
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8301400/ https://www.ncbi.nlm.nih.gov/pubmed/34356873 http://dx.doi.org/10.3390/biomedicines9070809

Ejemplares similares

Dissecting the Effect of a 3D Microscaffold on the Transcriptome of Neural Stem Cells with Computational Approaches: A Focus on Mechanotransduction
por: Rey, Federica, et al.
Publicado: (2020)

Neural precursors cells expanded in a 3D micro-engineered niche present enhanced therapeutic efficacy in vivo
por: Carelli, Stephana, et al.
Publicado: (2021)

Study of lncRNAs in Pediatric Neurological Diseases: Methods, Analysis of the State-of-Art and Possible Therapeutic Implications
por: Pandini, Cecilia, et al.
Publicado: (2023)

HuR interacts with lincBRN1a and lincBRN1b during neuronal stem cells differentiation
por: Carelli, Stephana, et al.
Publicado: (2019)

A New Selective PPARγ Modulator Inhibits Triglycerides Accumulation during Murine Adipocytes’ and Human Adipose-Derived Mesenchymal Stem Cells Differentiation
por: Al Haj, Ghina, et al.
Publicado: (2020)

Advances in Tissue Engineering and Innovative Fabrication Techniques for 3-D-Structures: Translational Applications in Neurodegenerative Diseases
por: Rey, Federica, et al.
Publicado: (2020)

Erythropoietin as a Neuroprotective Molecule: An Overview of Its Therapeutic Potential in Neurodegenerative Diseases
por: Rey, Federica, et al.
Publicado: (2019)

Mitochondrial Metabolism as Target of the Neuroprotective Role of Erythropoietin in Parkinson’s Disease
por: Rey, Federica, et al.
Publicado: (2021)

Transcriptome Analysis of Subcutaneous Adipose Tissue from Severely Obese Patients Highlights Deregulation Profiles in Coding and Non-Coding Oncogenes
por: Rey, Federica, et al.
Publicado: (2021)

Counteracting neuroinflammation in experimental Parkinson’s disease favors recovery of function: effects of Er-NPCs administration
por: Carelli, Stephana, et al.
Publicado: (2018)

Neuroprotection, Recovery of Function and Endogenous Neurogenesis in Traumatic Spinal Cord Injury Following Transplantation of Activated Adipose Tissue
por: Carelli, Stephana, et al.
Publicado: (2019)

Brain adaptation to hypoxia and hyperoxia in mice
por: Terraneo, Laura, et al.
Publicado: (2016)

SOD1 in Amyotrophic Lateral Sclerosis: “Ambivalent” Behavior Connected to the Disease
por: Pansarasa, Orietta, et al.
Publicado: (2018)

Alzheimer’s, Parkinson’s Disease and Amyotrophic Lateral Sclerosis Gene Expression Patterns Divergence Reveals Different Grade of RNA Metabolism Involvement
por: Garofalo, Maria, et al.
Publicado: (2020)

SNCA-AS1 in aging and Parkinson’s disease
por: Carelli, Stephana, et al.
Publicado: (2022)

Neural Precursor Cells Expanded Inside the 3D Micro-Scaffold Nichoid Present Different Non-Coding RNAs Profiles and Transcript Isoforms Expression: Possible Epigenetic Modulation by 3D Growth
por: Messa, Letizia, et al.
Publicado: (2021)

Deregulated expression of cytoskeleton related genes in the spinal cord and sciatic nerve of presymptomatic SOD1(G93A) Amyotrophic Lateral Sclerosis mouse model
por: Maximino, Jessica R., et al.
Publicado: (2014)

Patients’ Stem Cells Differentiation in a 3D Environment as a Promising Experimental Tool for the Study of Amyotrophic Lateral Sclerosis
por: Scarian, Eveljn, et al.
Publicado: (2022)

Mitochondrial dysfunctions in neurodegenerative diseases: role in disease pathogenesis, strategies for analysis and therapeutic prospects
por: Rey, Federica, et al.
Publicado: (2021)

Biomaterials in Neurodegenerative Disorders: A Promising Therapeutic Approach
por: Bordoni, Matteo, et al.
Publicado: (2020)

Grafted Neural Precursors Integrate Into Mouse Striatum, Differentiate and Promote Recovery of Function Through Release of Erythropoietin in MPTP-Treated Mice
por: Carelli, Stephana, et al.
Publicado: (2016)

Adaptive Immune Neuroprotection in G93A-SOD1 Amyotrophic Lateral Sclerosis Mice
por: Banerjee, Rebecca, et al.
Publicado: (2008)

Recurrently deregulated lncRNAs in hepatocellular carcinoma
por: Yang, Yang, et al.
Publicado: (2017)

From Neuronal Differentiation of iPSCs to 3D Neuro-Organoids: Modelling and Therapy of Neurodegenerative Diseases
por: Bordoni, Matteo, et al.
Publicado: (2018)

RNA Molecular Signature Profiling in PBMCs of Sporadic ALS Patients: HSP70 Overexpression Is Associated with Nuclear SOD1
por: Garofalo, Maria, et al.
Publicado: (2022)

Neuroprotective Effect of Bexarotene in the SOD1(G93A) Mouse Model of Amyotrophic Lateral Sclerosis
por: Riancho, Javier, et al.
Publicado: (2015)

Repurposing of Trimetazidine for amyotrophic lateral sclerosis: A study in SOD1(G93A) mice
por: Scaricamazza, Silvia, et al.
Publicado: (2022)

Comparing therapeutic modulators of the SOD1 G93A Amyotrophic Lateral Sclerosis mouse pathophysiology
por: Lee, Albert J. B., et al.
Publicado: (2023)

Lack of Effect of Methylene Blue in the SOD1 G93A Mouse Model of Amyotrophic Lateral Sclerosis
por: Lougheed, Rosamond, et al.
Publicado: (2011)

Comparative study of behavioural tests in the SOD1G93A mouse model of amyotrophic lateral sclerosis
por: OLIVÁN, Sara, et al.
Publicado: (2014)

Measuring Neuromuscular Junction Functionality in the SOD1(G93A) Animal Model of Amyotrophic Lateral Sclerosis
por: Rizzuto, Emanuele, et al.
Publicado: (2015)

α‐Synuclein antisense transcript SNCA‐AS1 regulates synapses‐ and aging‐related genes suggesting its implication in Parkinson's disease
por: Rey, Federica, et al.
Publicado: (2021)

Nuclear Phospho-SOD1 Protects DNA from Oxidative Stress Damage in Amyotrophic Lateral Sclerosis
por: Bordoni, Matteo, et al.
Publicado: (2019)

Dysregulation of the complement cascade in the hSOD1(G93A) transgenic mouse model of amyotrophic lateral sclerosis
por: Lee, John D, et al.
Publicado: (2013)

Effects of Ovariectomy in an hSOD1-G93A Transgenic Mouse Model of Amyotrophic Lateral Sclerosis (ALS)
por: Yan, Lina, et al.
Publicado: (2018)

The transcription factor Nurr1 is upregulated in amyotrophic lateral sclerosis patients and SOD1-G93A mice
por: Valsecchi, Valeria, et al.
Publicado: (2020)

MPO/HOCl Facilitates Apoptosis and Ferroptosis in the SOD1(G93A) Motor Neuron of Amyotrophic Lateral Sclerosis
por: Peng, Jialing, et al.
Publicado: (2022)

Targeting autotaxin impacts disease advance in the SOD1‐G93A mouse model of amyotrophic lateral sclerosis
por: Gento‐Caro, Ángela, et al.
Publicado: (2021)

Sex and HDAC4 Differently Affect the Pathophysiology of Amyotrophic Lateral Sclerosis in SOD1-G93A Mice
por: Renzini, Alessandra, et al.
Publicado: (2022)

Enhanced Function and Overexpression of Metabotropic Glutamate Receptors 1 and 5 in the Spinal Cord of the SOD1(G93A) Mouse Model of Amyotrophic Lateral Sclerosis during Disease Progression
por: Bonifacino, Tiziana, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_amfh5se3kscs6t9c4sd1kdsmhk