Cargando…

Different Within-Host Viral Evolution Dynamics in Severely Immunosuppressed Cases with Persistent SARS-CoV-2

A successful Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) variant, B.1.1.7, has recently been reported in the UK, causing global alarm. Most likely, the new variant emerged in a persistently infected patient, justifying a special focus on these cases. Our aim in this study was to exp...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pérez-Lago, Laura, Aldámiz-Echevarría, Teresa, García-Martínez, Rita, Pérez-Latorre, Leire, Herranz, Marta, Sola-Campoy, Pedro J., Suárez-González, Julia, Martínez-Laperche, Carolina, Comas, Iñaki, González-Candelas, Fernando, Catalán, Pilar, Muñoz, Patricia, García de Viedma, Darío
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8301427/ https://www.ncbi.nlm.nih.gov/pubmed/34356872 http://dx.doi.org/10.3390/biomedicines9070808

Ejemplares similares

Complete Analysis of the Epidemiological Scenario around a SARS-CoV-2 Reinfection: Previous Infection Events and Subsequent Transmission
por: Pérez Lago, Laura, et al.
Publicado: (2021)

Host Genetic Analysis Should Be Mandatory for Proper Classification of COVID-19 Reinfections
por: Pérez-Lago, Laura, et al.
Publicado: (2021)

Systematic Genomic and Clinical Analysis of Severe Acute Respiratory Syndrome Coronavirus 2 Reinfections and Recurrences Involving the Same Strain
por: Rodríguez-Grande, Cristina, et al.
Publicado: (2022)

Post-COVID-19 syndrome. SARS-CoV-2 RNA detection in plasma, stool, and urine in patients with persistent symptoms after COVID-19
por: Tejerina, Francisco, et al.
Publicado: (2022)

The relevance of multiple clinical specimens in the diagnosis of monkeypox virus, Spain, June 2022
por: Veintimilla, Cristina, et al.
Publicado: (2022)

Overlapping of Independent SARS-CoV-2 Nosocomial Transmissions in a Complex Outbreak
por: Pérez-Lago, Laura, et al.
Publicado: (2021)

In-Depth Characterization and Functional Analysis of Clonal Variants in a Mycobacterium tuberculosis Strain Prone to Microevolution
por: Navarro, Yurena, et al.
Publicado: (2017)

Systematic genomic analysis of SARS-CoV-2 co-infections throughout the pandemic and segregation of the strains involved
por: Peñas-Utrilla, Daniel, et al.
Publicado: (2023)

Early SARS-CoV-2 Reinfections Involving the Same or Different Genomic Lineages, Spain
por: Rodríguez-Grande, Cristina, et al.
Publicado: (2023)

Mycobacterium tuberculosis Acquires Limited Genetic Diversity in Prolonged Infections, Reactivations and Transmissions Involving Multiple Hosts
por: Herranz, Marta, et al.
Publicado: (2018)

Alternative molecular and genomic strategies to provide a rapid response to alerts concerning the introduction of new emerging SARS-CoV-2 variants: the Omicron alert
por: Herranz, Marta, et al.
Publicado: (2023)

First importations of SARS-CoV-2 P.1 and P.2 variants from Brazil to Spain and early community transmission
por: Sola Campoy, Pedro J., et al.
Publicado: (2022)

First importations of SARS-CoV-2 P.1 and P.2 variants from Brazil to Spain and early community transmission
por: Sola Campoy, Pedro J., et al.
Publicado: (2022)

Whole genome sequencing–based analysis of tuberculosis (TB) in migrants: rapid tools for cross-border surveillance and to distinguish between recent transmission in the host country and new importations
por: Abascal, Estefanía, et al.
Publicado: (2019)

Detection of Minority Variants and Mixed Infections in Mycobacterium tuberculosis by Direct Whole-Genome Sequencing on Noncultured Specimens Using a Specific-DNA Capture Strategy
por: Lozano, Nuria, et al.
Publicado: (2021)

Insights into the Complexity of a Dormant Mycobacterium tuberculosis Cluster Once Transmission Is Resumed
por: Acosta, Fermin, et al.
Publicado: (2022)

Erratum for Acosta et al., “Insights into the Complexity of a Dormant Mycobacterium tuberculosis Cluster Once Transmission Is Resumed”
por: Acosta, Fermin, et al.
Publicado: (2022)

Co-infection with Drug-Susceptible and Reactivated Latent Multidrug-Resistant Mycobacterium tuberculosis
por: Pérez-Lago, Laura, et al.
Publicado: (2015)

Unraveling the evolutionary history of the phosphoryl-transfer chain of the phosphoenolpyruvate:phosphotransferase system through phylogenetic analyses and genome context
por: Comas, Iñaki, et al.
Publicado: (2008)

Phylogenetic signal and functional categories in Proteobacteria genomes
por: Comas, Iñaki, et al.
Publicado: (2007)

Validating viral quasispecies with digital organisms: a re-examination of the critical mutation rate
por: Comas, Iñaki, et al.
Publicado: (2005)

Nosocomial Transmission of SARS-CoV-2 Involving Vaccinated Health Care Workers
por: Pérez-Lago, Laura, et al.
Publicado: (2022)

Inference of Active Viral Replication in Cases with Sustained Positive Reverse Transcription-PCR Results for SARS-CoV-2
por: Rodríguez-Grande, Cristina, et al.
Publicado: (2021)

European mitochondrial haplogroups predict liver-related outcomes in patients coinfected with HIV and HCV: a retrospective study
por: Aldámiz-Echevarría, Teresa, et al.
Publicado: (2019)

Gene expression models based on a reference laboratory strain are poor predictors of Mycobacterium tuberculosis complex transcriptional diversity
por: Chiner-Oms, Álvaro, et al.
Publicado: (2018)

A mutation responsible for impaired detection by the Xpert SARS-CoV-2 assay independently emerged in different lineages during the SARS-CoV-2 pandemic
por: Peñas-Utrilla, Daniel, et al.
Publicado: (2023)

Exportation of MDR TB to Europe from Setting with Actively Transmitted Persistent Strains in Peru
por: Acosta, Fermín, et al.
Publicado: (2019)

Rapid Identification of Relevant Microbial Strains by Identifying Multiple Marker Single Nucleotide Polymorphisms via Amplicon Sequencing: Epidemic Monkeypox Virus as a Proof of Concept
por: Buenestado-Serrano, Sergio, et al.
Publicado: (2023)

Soluble Adhesion Molecules in Patients Coinfected with HIV and HCV: A Predictor of Outcome
por: Aldámiz-Echevarría, Teresa, et al.
Publicado: (2016)

Prognostic Value of Transient Elastography in Human Immunodeficiency Virus-Infected Patients With Chronic Hepatitis C
por: Pérez-Latorre, Leire, et al.
Publicado: (2016)

Screening of inmates transferred to Spain reveals a Peruvian prison as a reservoir of persistent Mycobacterium tuberculosis MDR strains and mixed infections
por: Abascal, Estefanía, et al.
Publicado: (2020)

SARS-CoV-2 B.1.1.7 Decline Is Not Driven by the Introduction of a More Successful Variant
por: Rodríguez-Grande, Cristina, et al.
Publicado: (2021)

Shared Mutations in Emerging SARS-CoV-2 Circulating Variants May Lead to Reverse Transcription-PCR (RT-PCR)-Based Misidentification of B.1.351 and P.1 Variants of Concern
por: Losada, Carmen, et al.
Publicado: (2021)

Common gene expression strategies revealed by genome-wide analysis in yeast
por: García-Martínez, José, et al.
Publicado: (2007)

Demographic, clinical and microbiological characteristics of the first 30 human monkeypox confirmed cases attended in a tertiary hospital in Madrid (Spain), during the May-June 2022 international outbreak
por: Cobos, Alejandro, et al.
Publicado: (2023)

Optimizing and accelerating the assignation of lineages in Mycobacterium tuberculosis using novel alternative single-tube assays
por: Carcelén, María, et al.
Publicado: (2017)

The first 100 cases of COVID-19 in a Hospital in Madrid with a 2-month follow-up
por: Muñoz, Patricia, et al.
Publicado: (2020)

Evaluation of the new advanced 15-loci MIRU-VNTR genotyping tool in Mycobacterium tuberculosis molecular epidemiology studies
por: Alonso-Rodríguez, Noelia, et al.
Publicado: (2008)

Frequent Emergence of Resistance Mutations Following Complex Intra-Host Genomic Dynamics in SARS-CoV-2 Patients Receiving Sotrovimab
por: Palomino-Cabrera, Rosalía, et al.
Publicado: (2023)

Simplified Model to Survey Tuberculosis Transmission in Countries Without Systematic Molecular Epidemiology Programs
por: Domínguez, Juan, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_cp4ha8rf036tm54q7t9den881e