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Rifamycin W Analogues from Amycolatopsis mediterranei S699 Δrif-orf5 Strain

Rifamycin W, the most predominant intermediate in the biosynthesis of rifamycin, needs to undergo polyketide backbone rearrangement to produce rifamycin B via an oxidative cleavage of the C-12/C-29 double bond. However, the mechanism of this putative oxidative cleavage has not been characterized yet...

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Detalles Bibliográficos
Autores principales: Shi, Yanrong, Ye, Feng, Song, Yuliang, Zhang, Xiaochun, Lu, Chunhua, Shen, Yuemao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8301457/
https://www.ncbi.nlm.nih.gov/pubmed/34206314
http://dx.doi.org/10.3390/biom11070920