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Neuroinflammation in Ischemic Stroke: Inhibition of cAMP-Specific Phosphodiesterases (PDEs) to the Rescue
Ischemic stroke is caused by a thromboembolic occlusion of a major cerebral artery, with the impaired blood flow triggering neuroinflammation and subsequent neuronal damage. Both the innate immune system (e.g., neutrophils, monocytes/macrophages) in the acute ischemic stroke phase and the adaptive i...
Autores principales: | Ponsaerts, Laura, Alders, Lotte, Schepers, Melissa, de Oliveira, Rúbia Maria Weffort, Prickaerts, Jos, Vanmierlo, Tim, Bronckaers, Annelies |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8301462/ https://www.ncbi.nlm.nih.gov/pubmed/34206420 http://dx.doi.org/10.3390/biomedicines9070703 |
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