The Dual Role of a Polyvalent IgM/IgA-Enriched Immunoglobulin Preparation in Activating and Inhibiting the Complement System

Activation of the complement system is important for efficient clearance of a wide variety of pathogens via opsonophagocytosis, or by direct lysis via complement-dependent cytotoxicity (CDC). However, in severe infections dysregulation of the complement system contributes to hyperinflammation. The i...

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Detalles Bibliográficos
Autores principales: Schmidt, Carolin, Weißmüller, Sabrina, Bohländer, Fabian, Germer, Matthias, König, Martin, Staus, Alexander, Wartenberg-Demand, Andrea, Heinz, Corina C., Schüttrumpf, Jörg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8301464/
https://www.ncbi.nlm.nih.gov/pubmed/34356880
http://dx.doi.org/10.3390/biomedicines9070817

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8301464/
https://www.ncbi.nlm.nih.gov/pubmed/34356880
http://dx.doi.org/10.3390/biomedicines9070817

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