Biopsy-Proven Lymphocytic Myocarditis With Heart Failure in a Middle-Aged Female Patient With Mixed Connective Tissue Disease

A 56-year-old woman with mixed connective tissue disease, who was on maintenance immunosuppression, developed asymptomatic left ventricular dysfunction, ventricular arrhythmia, and high troponin I. Heart catheterization showed normal coronaries and biopsy-proven, virus-negative lymphocytic myocardit...

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Autores principales: Figliozzi, Stefano, Rizzo, Stefania, Cheng, Chun-Yan, Iliceto, Sabino, Basso, Cristina, Caforio, Alida L.P., Marcolongo, Renzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8301497/
https://www.ncbi.nlm.nih.gov/pubmed/34316778
http://dx.doi.org/10.1016/j.jaccas.2019.05.032
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author Figliozzi, Stefano
Rizzo, Stefania
Cheng, Chun-Yan
Iliceto, Sabino
Basso, Cristina
Caforio, Alida L.P.
Marcolongo, Renzo
author_facet Figliozzi, Stefano
Rizzo, Stefania
Cheng, Chun-Yan
Iliceto, Sabino
Basso, Cristina
Caforio, Alida L.P.
Marcolongo, Renzo
author_sort Figliozzi, Stefano
collection PubMed
description A 56-year-old woman with mixed connective tissue disease, who was on maintenance immunosuppression, developed asymptomatic left ventricular dysfunction, ventricular arrhythmia, and high troponin I. Heart catheterization showed normal coronaries and biopsy-proven, virus-negative lymphocytic myocarditis. A biopsy-guided immunosuppression upgrade effectively treated autoimmune myocarditis, which resulted in ventricular function recovery, resolution of arrhythmia, and of troponin release. (Level of Difficulty: Advanced.)
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spelling pubmed-83014972021-07-26 Biopsy-Proven Lymphocytic Myocarditis With Heart Failure in a Middle-Aged Female Patient With Mixed Connective Tissue Disease Figliozzi, Stefano Rizzo, Stefania Cheng, Chun-Yan Iliceto, Sabino Basso, Cristina Caforio, Alida L.P. Marcolongo, Renzo JACC Case Rep Case Report A 56-year-old woman with mixed connective tissue disease, who was on maintenance immunosuppression, developed asymptomatic left ventricular dysfunction, ventricular arrhythmia, and high troponin I. Heart catheterization showed normal coronaries and biopsy-proven, virus-negative lymphocytic myocarditis. A biopsy-guided immunosuppression upgrade effectively treated autoimmune myocarditis, which resulted in ventricular function recovery, resolution of arrhythmia, and of troponin release. (Level of Difficulty: Advanced.) Elsevier 2019-08-21 /pmc/articles/PMC8301497/ /pubmed/34316778 http://dx.doi.org/10.1016/j.jaccas.2019.05.032 Text en © 2019 Published by Elsevier on behalf of the American College of Cardiology Foundation. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Figliozzi, Stefano
Rizzo, Stefania
Cheng, Chun-Yan
Iliceto, Sabino
Basso, Cristina
Caforio, Alida L.P.
Marcolongo, Renzo
Biopsy-Proven Lymphocytic Myocarditis With Heart Failure in a Middle-Aged Female Patient With Mixed Connective Tissue Disease
title Biopsy-Proven Lymphocytic Myocarditis With Heart Failure in a Middle-Aged Female Patient With Mixed Connective Tissue Disease
title_full Biopsy-Proven Lymphocytic Myocarditis With Heart Failure in a Middle-Aged Female Patient With Mixed Connective Tissue Disease
title_fullStr Biopsy-Proven Lymphocytic Myocarditis With Heart Failure in a Middle-Aged Female Patient With Mixed Connective Tissue Disease
title_full_unstemmed Biopsy-Proven Lymphocytic Myocarditis With Heart Failure in a Middle-Aged Female Patient With Mixed Connective Tissue Disease
title_short Biopsy-Proven Lymphocytic Myocarditis With Heart Failure in a Middle-Aged Female Patient With Mixed Connective Tissue Disease
title_sort biopsy-proven lymphocytic myocarditis with heart failure in a middle-aged female patient with mixed connective tissue disease
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8301497/
https://www.ncbi.nlm.nih.gov/pubmed/34316778
http://dx.doi.org/10.1016/j.jaccas.2019.05.032
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