Cargando…
Pharmacokinetics and tolerability of apremilast in healthy Korean adult men
We performed a two‐part study to evaluate the pharmacokinetics, safety, and tolerability of oral apremilast, a phosphodiesterase 4 inhibitor indicated for the treatment of psoriasis, in healthy Korean adult men. In part 1, there were 12 subjects who randomly received a single oral dose of apremilast...
Autores principales: | Huh, Ki Young, Choi, Yewon, Nissel, Jim, Palmisano, Maria, Wang, Xiaomin, Liu, Liangang, Ramirez‐Valle, Francisco, Lee, Howard |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8301552/ https://www.ncbi.nlm.nih.gov/pubmed/33932093 http://dx.doi.org/10.1111/cts.13013 |
Ejemplares similares
-
Impact of Renal Impairment on the Pharmacokinetics of Apremilast and Metabolite M12
por: Liu, Yong, et al.
Publicado: (2016) -
The pharmacokinetic effect of coadministration of apremilast and methotrexate in individuals with rheumatoid arthritis and psoriatic arthritis
por: Liu, Yong, et al.
Publicado: (2014) -
The impact of co-administration of ketoconazole and rifampicin on the pharmacokinetics of apremilast in healthy volunteers
por: Liu, Yong, et al.
Publicado: (2014) -
The effects of apremilast on the QTc interval in healthy male volunteers: a formal, thorough QT study
por: Palmisano, Maria, et al.
Publicado: (2016) -
Population Pharmacokinetics of Pomalidomide
por: Li, Yan, et al.
Publicado: (2015)