Lipid droplet screen in human hepatocytes identifies TRRAP as a regulator of cellular triglyceride metabolism

Hepatocytes store triglycerides (TGs) in the form of lipid droplets (LDs), which are increased in hepatosteatosis. The regulation of hepatic LDs is poorly understood and new therapies to reduce hepatosteatosis are needed. We performed a siRNA kinase and phosphatase screen in HuH‐7 cells using high‐c...

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Detalles Bibliográficos
Autores principales: Abbey, Deepti, Conlon, Donna, Rainville, Christopher, Elwyn, Susannah, Quiroz‐Figueroa, Katherine, Billheimer, Jeffrey, Schultz, David C., Hand, Nicholas J., Cherry, Sara, Rader, Daniel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8301584/
https://www.ncbi.nlm.nih.gov/pubmed/34156146
http://dx.doi.org/10.1111/cts.12988

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8301584/
https://www.ncbi.nlm.nih.gov/pubmed/34156146
http://dx.doi.org/10.1111/cts.12988

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