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Interference of Polydatin/Resveratrol in the ACE2:Spike Recognition during COVID-19 Infection. A Focus on Their Potential Mechanism of Action through Computational and Biochemical Assays

In the search for new therapeutic strategies to contrast SARS-CoV-2, we here studied the interaction of polydatin (PD) and resveratrol (RESV)—two natural stilbene polyphenols with manifold, well known biological activities—with Spike, the viral protein essential for virus entry into host cells, and...

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Detalles Bibliográficos
Autores principales:	Perrella, Fulvio, Coppola, Federico, Petrone, Alessio, Platella, Chiara, Montesarchio, Daniela, Stringaro, Annarita, Ravagnan, Giampietro, Fuggetta, Maria Pia, Rega, Nadia, Musumeci, Domenica
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8301781/ https://www.ncbi.nlm.nih.gov/pubmed/34356672 http://dx.doi.org/10.3390/biom11071048

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