TGF-β1 Receptor Inhibitor SB525334 Attenuates the Epithelial to Mesenchymal Transition of Peritoneal Mesothelial Cells via the TGF-β1 Signaling Pathway

We investigated the effect of SB525334 (TGF-β receptor type 1 (TβRI) inhibitor) on the epithelial to mesenchymal transition (EMT) signaling pathway in human peritoneal mesothelial cells (HPMCs) and a peritoneal fibrosis mouse model. In vitro experiments were performed using HPMCs. HPMCs were treated...

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Detalles Bibliográficos
Autores principales: Heo, Jung-Yoon, Do, Jun-Young, Lho, Yunmee, Kim, A-Young, Kim, Sang-Woon, Kang, Seok-Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8301792/
https://www.ncbi.nlm.nih.gov/pubmed/34356903
http://dx.doi.org/10.3390/biomedicines9070839

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8301792/
https://www.ncbi.nlm.nih.gov/pubmed/34356903
http://dx.doi.org/10.3390/biomedicines9070839

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