Cargando…
Exploration of the Activation Mechanism of the Epigenetic Regulator MLL3: A QM/MM Study
The mixed lineage leukemia 3 or MLL3 is the enzyme in charge of the writing of an epigenetic mark through the methylation of lysine 4 from the N-terminal domain of histone 3 and its deregulation has been related to several cancer lines. An interesting feature of this enzyme comes from its regulation...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2021
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8301819/ https://www.ncbi.nlm.nih.gov/pubmed/34356675 http://dx.doi.org/10.3390/biom11071051 |