The Role of Resolvins, Protectins and Marensins in Non-Alcoholic Fatty Liver Disease (NAFLD)

Increased triacylglycerols’ (TAG) synthesis, insulin resistance, and prolonged liver lipid storage might lead to the development of non-alcoholic fatty liver disease (NAFLD). Global prevalence of NAFLD has been estimated to be around 25%, with gradual elevation of this ratio along with the increased...

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Autores principales: Maciejewska-Markiewicz, Dominika, Stachowska, Ewa, Hawryłkowicz, Viktoria, Stachowska, Laura, Prowans, Piotr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8301825/
https://www.ncbi.nlm.nih.gov/pubmed/34202667
http://dx.doi.org/10.3390/biom11070937
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author Maciejewska-Markiewicz, Dominika
Stachowska, Ewa
Hawryłkowicz, Viktoria
Stachowska, Laura
Prowans, Piotr
author_facet Maciejewska-Markiewicz, Dominika
Stachowska, Ewa
Hawryłkowicz, Viktoria
Stachowska, Laura
Prowans, Piotr
author_sort Maciejewska-Markiewicz, Dominika
collection PubMed
description Increased triacylglycerols’ (TAG) synthesis, insulin resistance, and prolonged liver lipid storage might lead to the development of non-alcoholic fatty liver disease (NAFLD). Global prevalence of NAFLD has been estimated to be around 25%, with gradual elevation of this ratio along with the increased content of adipose tissue in a body. The initial stages of NAFLD may be reversible, but the exposition to pathological factors should be limited. As dietary factors greatly influence various disease development, scientists try to find dietary components, helping to alleviate the steatosis. These components include n-3 polyunsaturated (PUFA) fatty acids, especially eicosapentaenoic acid (EPA) and docosahexaenoic acids (DHA). This review focused on the role of resolvins, protectins and merensins in NAFLD.
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spelling pubmed-83018252021-07-24 The Role of Resolvins, Protectins and Marensins in Non-Alcoholic Fatty Liver Disease (NAFLD) Maciejewska-Markiewicz, Dominika Stachowska, Ewa Hawryłkowicz, Viktoria Stachowska, Laura Prowans, Piotr Biomolecules Communication Increased triacylglycerols’ (TAG) synthesis, insulin resistance, and prolonged liver lipid storage might lead to the development of non-alcoholic fatty liver disease (NAFLD). Global prevalence of NAFLD has been estimated to be around 25%, with gradual elevation of this ratio along with the increased content of adipose tissue in a body. The initial stages of NAFLD may be reversible, but the exposition to pathological factors should be limited. As dietary factors greatly influence various disease development, scientists try to find dietary components, helping to alleviate the steatosis. These components include n-3 polyunsaturated (PUFA) fatty acids, especially eicosapentaenoic acid (EPA) and docosahexaenoic acids (DHA). This review focused on the role of resolvins, protectins and merensins in NAFLD. MDPI 2021-06-24 /pmc/articles/PMC8301825/ /pubmed/34202667 http://dx.doi.org/10.3390/biom11070937 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Communication
Maciejewska-Markiewicz, Dominika
Stachowska, Ewa
Hawryłkowicz, Viktoria
Stachowska, Laura
Prowans, Piotr
The Role of Resolvins, Protectins and Marensins in Non-Alcoholic Fatty Liver Disease (NAFLD)
title The Role of Resolvins, Protectins and Marensins in Non-Alcoholic Fatty Liver Disease (NAFLD)
title_full The Role of Resolvins, Protectins and Marensins in Non-Alcoholic Fatty Liver Disease (NAFLD)
title_fullStr The Role of Resolvins, Protectins and Marensins in Non-Alcoholic Fatty Liver Disease (NAFLD)
title_full_unstemmed The Role of Resolvins, Protectins and Marensins in Non-Alcoholic Fatty Liver Disease (NAFLD)
title_short The Role of Resolvins, Protectins and Marensins in Non-Alcoholic Fatty Liver Disease (NAFLD)
title_sort role of resolvins, protectins and marensins in non-alcoholic fatty liver disease (nafld)
topic Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8301825/
https://www.ncbi.nlm.nih.gov/pubmed/34202667
http://dx.doi.org/10.3390/biom11070937
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