Cargando…

A Metalloproteinase Induces an Inflammatory Response in Preadipocytes with the Activation of COX Signalling Pathways and Participation of Endogenous Phospholipases A(2)

Matrix metalloproteinases (MMPs) are proteolytic enzymes that have been associated with the pathogenesis of inflammatory diseases and obesity. Adipose tissue in turn is an active endocrine organ capable of secreting a range of proinflammatory mediators with autocrine and paracrine properties, which...

Descripción completa

Detalles Bibliográficos
Autores principales:	Janovits, Priscila Motta, Leiguez, Elbio, Portas, Viviane, Teixeira, Catarina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8301905/ https://www.ncbi.nlm.nih.gov/pubmed/34206390 http://dx.doi.org/10.3390/biom11070921

Ejemplares similares

Bothrops moojeni snake venom induces an inflammatory response in preadipocytes: Insights into a new aspect of envenomation
por: Maia-Marques, Rodrigo, et al.
Publicado: (2022)

Inflammatory Effects of Bothrops Phospholipases A(2): Mechanisms Involved in Biosynthesis of Lipid Mediators and Lipid Accumulation
por: Moreira, Vanessa, et al.
Publicado: (2021)

A Representative GIIA Phospholipase A(2) Activates Preadipocytes to Produce Inflammatory Mediators Implicated in Obesity Development
por: Leiguez, Elbio, et al.
Publicado: (2020)

A Lipidomic Perspective of the Action of Group IIA Secreted Phospholipase A(2) on Human Monocytes: Lipid Droplet Biogenesis and Activation of Cytosolic Phospholipase A(2)α
por: Rodríguez, Juan P., et al.
Publicado: (2020)

Crotalus durissus ruruima Snake Venom and a Phospholipase A(2) Isolated from This Venom Elicit Macrophages to Form Lipid Droplets and Synthesize Inflammatory Lipid Mediators
por: de Carvalho, Ana Eduarda Zulim, et al.
Publicado: (2019)

A representative metalloprotease induces PGE(2) synthesis in fibroblast-like synoviocytes via the NF-κB/COX-2 pathway with amplification by IL-1β and the EP4 receptor
por: Viana, Mariana N., et al.
Publicado: (2020)

A Lys49 Phospholipase A(2), Isolated from Bothrops asper Snake Venom, Induces Lipid Droplet Formation in Macrophages Which Depends on Distinct Signaling Pathways and the C-Terminal Region
por: Cristina Giannotti, Karina, et al.
Publicado: (2013)

A Snake Venom-Secreted Phospholipase A(2) Induces Foam Cell Formation Depending on the Activation of Factors Involved in Lipid Homeostasis
por: Leiguez, Elbio, et al.
Publicado: (2018)

A Secreted Phospholipase A(2) Induces Formation of Smooth Muscle Foam Cells Which Transdifferentiate to Macrophage-Like State
por: Giannotti, Karina Cristina, et al.
Publicado: (2019)

Critical Role of TLR2 and MyD88 for Functional Response of Macrophages to a Group IIA-Secreted Phospholipase A(2) from Snake Venom
por: Leiguez, Elbio, et al.
Publicado: (2014)

Inflammation Induced by Platelet-Activating Viperid Snake Venoms: Perspectives on Thromboinflammation
por: Teixeira, Catarina, et al.
Publicado: (2019)

Myostatin increases the expression of matrix metalloproteinase genes to promote preadipocytes differentiation in pigs
por: Zhu, Zhe, et al.
Publicado: (2022)

A snake venom group IIA PLA(2) with immunomodulatory activity induces formation of lipid droplets containing 15-d-PGJ(2) in macrophages
por: Giannotti, Karina Cristina, et al.
Publicado: (2017)

Flavocoxid Inhibits Phospholipase A2, Peroxidase Moieties of the Cyclooxygenases (COX), and 5-Lipoxygenase, Modifies COX-2 Gene Expression, and Acts as an Antioxidant
por: Burnett, Bruce P., et al.
Publicado: (2011)

Identification of Long Non-Coding RNA-Associated Competing Endogenous RNA Network in the Differentiation of Chicken Preadipocytes
por: Chen, Lan, et al.
Publicado: (2019)

Effects of puerarin on the Akt signaling pathway in bovine preadipocyte differentiation
por: Yun, Jinyan, et al.
Publicado: (2020)

Stages of preadipocyte differentiation: biomarkers and pathways for extracellular structural remodeling
por: Hu, Zhihan, et al.
Publicado: (2022)

Participation of COX-1 and COX-2 in the contractile effect of phenylephrine in prepubescent and old rats
por: Guevara-Balcazar, Gustavo, et al.
Publicado: (2017)

Endogenous phospholipase A(2) inhibitors in snakes: a brief overview
por: Campos, Patrícia Cota, et al.
Publicado: (2016)

Sphingomyelinases D From Loxosceles Spider Venoms and Cell Membranes: Action on Lipid Rafts and Activation of Endogenous Metalloproteinases
por: Lopes, Priscila Hess, et al.
Publicado: (2020)

Articular inflammation induced by an enzymatically-inactive Lys49 phospholipase A(2): activation of endogenous phospholipases contributes to the pronociceptive effect
por: Dias, Renata Gonçalves, et al.
Publicado: (2017)

KLF7 promotes preadipocyte proliferation via activation of the Akt signaling pathway by Cis-regulating CDKN3 : KLF7 promotes preadipocyte proliferation by activating Akt pathway
por: Jia, Ziqiu, et al.
Publicado: (2022)

Peanut sprout ethanol extract inhibits the adipocyte proliferation, differentiation, and matrix metalloproteinases activities in mouse fibroblast 3T3-L1 preadipocytes
por: Kim, Woo Kyoung, et al.
Publicado: (2013)

Membrane metallo-endopeptidase (Neprilysin) regulates inflammatory response and insulin signaling in white preadipocytes
por: Ramirez, Alfred K., et al.
Publicado: (2019)

Matrix Metalloproteinase‐2 Negatively Regulates Cardiac Secreted Phospholipase A(2) to Modulate Inflammation and Fever
por: Berry, Evan, et al.
Publicado: (2015)

The Contribution of Phospholipase A(2) and Metalloproteinases to the Synergistic Action of Viper Venom on the Bioenergetic Profile of Vero Cells
por: Ayvazyan, Naira, et al.
Publicado: (2022)

Epithelial-Cell-Derived Phospholipase A(2) Group 1B Is an Endogenous Anthelmintic
por: Entwistle, Lewis J., et al.
Publicado: (2017)

Ginkgo biloba Extract Stimulates Adipogenesis in 3T3-L1 Preadipocytes
por: Thomaz, Fernanda Malanconi, et al.
Publicado: (2022)

Resveratrol inhibits the protein expression of transcription factors related adipocyte differentiation and the activity of matrix metalloproteinase in mouse fibroblast 3T3-L1 preadipocytes
por: Kang, Nam E, et al.
Publicado: (2012)

Snake Venom Cytotoxins, Phospholipase A(2)s, and Zn(2+)-dependent Metalloproteinases: Mechanisms of Action and Pharmacological Relevance
por: Gasanov, Sardar E, et al.
Publicado: (2014)

Metalloproteinases in Inflammatory Bowel Diseases
por: Marônek, Martin, et al.
Publicado: (2021)

Investigating the Connection Between Endogenous Heme Accumulation and COX2 Activity in Cancer Cells
por: Destefanis, Francesca, et al.
Publicado: (2019)

Transcriptional Control of Preadipocyte Determination by Zfp423
por: Gupta, Rana K., et al.
Publicado: (2010)

Aging, Depot Origin, and Preadipocyte Gene Expression
por: Cartwright, Mark J., et al.
Publicado: (2010)

Brown preadipocyte transplantation locally ameliorates obesity
por: Takaya, Kento, et al.
Publicado: (2021)

C/EBPZ modulates the differentiation and proliferation of preadipocytes
por: Chen, Yuechan, et al.
Publicado: (2021)

Matrix metalloproteinase 14 participates in corneal lymphangiogenesis through the VEGF-C/VEGFR-3 signaling pathway
por: Du, Hai-Tao, et al.
Publicado: (2016)

The nonsense-mediated mRNA decay (NMD) pathway differentially regulates COX17, COX19 and COX23 mRNAs
por: Murtha, Kaitlin, et al.
Publicado: (2018)

Matrix Metalloproteinases and Tissue Inhibitor of Metalloproteinases Are Essential for the Inflammatory Response in Cancer Cells
por: Sun, Jun
Publicado: (2010)

Abundance of Circulating Preadipocyte Factor 1 in Early Life
por: de Zegher, Francis, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_080ml208hi0jdetipvbrt6eelq