Cargando…

ATGL Deficiency-Induced Triglyceride Deposit Cardiomyovasculopathy Requiring Heart Transplant: A 5-Year Follow-Up

A young man presented with syncope. He was diagnosed with triglyceride deposit cardiomyovasculopathy and skeletal myopathy secondary to adipose triglyceride lipase (ATGL) deficiency. Despite optimal medical therapy, he required heart transplantation to treat his heart failure. Five years post-transp...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rajani, Prina, Robertus, Jan Lukas, Wong, Joyce, Homfray, Tessa, Gil, Fernando Riesgo, Shanmuganathan, Mayooran
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2020
Materias:	Case Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8302057/ https://www.ncbi.nlm.nih.gov/pubmed/34317343 http://dx.doi.org/10.1016/j.jaccas.2020.03.021

Ejemplares similares

Triglyceride deposit cardiomyovasculopathy: a rare cardiovascular disorder
por: Li, Ming, et al.
Publicado: (2019)

Prevalence and clinical outcomes of triglyceride deposit cardiomyovasculopathy among haemodialysis patients
por: Onishi, Tomohiro, et al.
Publicado: (2021)

Remarkable regression of diffuse coronary atherosclerosis in patients with triglyceride deposit cardiomyovasculopathy
por: Hirano, Ken-ichi, et al.
Publicado: (2022)

Triglyceride Deposit Cardiomyovasculopathy with Massive Myocardial Triglyceride which Was Proven Using Proton-magnetic Resonance Spectroscopy
por: Sai, Eiryu, et al.
Publicado: (2020)

Association of Triglyceride Deposit Cardiomyovasculopathy With Drug-Eluting Stent Restenosis Among Patients With Diabetes
por: Nakano, Yusuke, et al.
Publicado: (2020)

Quantitative proteomic analysis of cultured skin fibroblast cells derived from patients with triglyceride deposit cardiomyovasculopathy
por: Hara, Yasuhiro, et al.
Publicado: (2013)

(1)H-MRS to evaluate improved triglyceride accumulation in idiopathic triglyceride deposit cardiomyovasculopathy after CNT-01 (tricaprin/trisdecanoin) administration
por: Aikawa, Tatsuro, et al.
Publicado: (2023)

A novel homozygous missense mutation in PNPLA2 in a patient manifesting primary triglyceride deposit cardiomyovasculopathy
por: Hara, Yasuhiro, et al.
Publicado: (2023)

Peripheral leukocyte anomaly detected with routine automated hematology analyzer sensitive to adipose triglyceride lipase deficiency manifesting neutral lipid storage disease with myopathy/triglyceride deposit cardiomyovasculopathy
por: Suzuki, Akira, et al.
Publicado: (2014)

Methods of calculating (123)I-β-methyl-P-iodophenyl-pentadecanoic acid washout rates in triglyceride deposit cardiomyovasculopathy
por: Chen, Zhuoqing, et al.
Publicado: (2022)

Blocking Lipid Uptake Pathways Does not Prevent Toxicity in Adipose Triglyceride Lipase (ATGL) Deficiency
por: Oluwadare, Jide, et al.
Publicado: (2022)

Of mice and men: The physiological role of adipose triglyceride lipase (ATGL)()
por: Schreiber, Renate, et al.
Publicado: (2019)

Interaction between the Triglyceride Lipase ATGL and the Arf1 Activator GBF1
por: Ellong, Emy Njoh, et al.
Publicado: (2011)

Structure–activity studies in the development of a hydrazone based inhibitor of adipose-triglyceride lipase (ATGL)
por: Mayer, Nicole, et al.
Publicado: (2015)

PEDF and PEDF-derived peptide 44mer stimulate cardiac triglyceride degradation via ATGL
por: Zhang, Hao, et al.
Publicado: (2015)

Adipose triglyceride lipase (ATGL) expression in human skeletal muscle is type I (oxidative) fiber specific
por: Jocken, Johan W. E., et al.
Publicado: (2008)

LncRNA SRA promotes hepatic steatosis through repressing the expression of adipose triglyceride lipase (ATGL)
por: Chen, Gang, et al.
Publicado: (2016)

Lipid Droplet-Associated Hydrolase Promotes Lipid Droplet Fusion and Enhances ATGL Degradation and Triglyceride Accumulation
por: Goo, Young-Hwa, et al.
Publicado: (2017)

Adipose triglyceride lipase (Atgl) mediates the antibiotic jinggangmycin-stimulated reproduction in the brown planthopper, Nilaparvata lugens Stål
por: Jiang, Yi-Ping, et al.
Publicado: (2016)

Recent Advances on the Role of ATGL in Cancer
por: Zhang, Renshuai, et al.
Publicado: (2022)

Measurement of ATGL activity using adiposomes
por: Ma, Xuejing, et al.
Publicado: (2023)

OSBPL2 Is Required for the Binding of COPB1 to ATGL and the Regulation of Lipid Droplet Lipolysis
por: Wang, Tianming, et al.
Publicado: (2020)

Regulation of G0/G1 Switch Gene 2 (G0S2) Protein Ubiquitination and Stability by Triglyceride Accumulation and ATGL Interaction
por: Heckmann, Bradlee L., et al.
Publicado: (2016)

Hints on ATGL implications in cancer: beyond bioenergetic clues
por: Vegliante, Rolando, et al.
Publicado: (2018)

Application of a sensitive collection heuristic for very large protein families: Evolutionary relationship between adipose triglyceride lipase (ATGL) and classic mammalian lipases
por: Schneider, Georg, et al.
Publicado: (2006)

The Minimal Domain of Adipose Triglyceride Lipase (ATGL) Ranges until Leucine 254 and Can Be Activated and Inhibited by CGI-58 and G0S2, Respectively
por: Cornaciu, Irina, et al.
Publicado: (2011)

Inhibition of adipose triglyceride lipase (ATGL) by the putative tumor suppressor G0S2 or a small molecule inhibitor attenuates the growth of cancer cells
por: Zagani, Rachid, et al.
Publicado: (2015)

Distinct roles for α-β hydrolase domain 5 (ABHD5/CGI-58) and adipose triglyceride lipase (ATGL/PNPLA2) in lipid metabolism and signaling
por: Lord, Caleb C., et al.
Publicado: (2012)

Effect of Global ATGL Knockout on Murine Fasting Glucose Kinetics
por: Coelho, Margarida, et al.
Publicado: (2015)

Enterocyte-specific ATGL overexpression affects intestinal and systemic cholesterol homeostasis(☆)
por: Korbelius, Melanie, et al.
Publicado: (2022)

ATGL and CGI-58 are lipid droplet proteins of the hepatic stellate cell line HSC-T6
por: Eichmann, Thomas O., et al.
Publicado: (2015)

ATGL deficiency aggravates pressure overload-triggered myocardial hypertrophic remodeling associated with the proteasome-PTEN-mTOR-autophagy pathway
por: Han, Xiao, et al.
Publicado: (2022)

Human Frame Shift Mutations Affecting the Carboxyl Terminus of Perilipin Increase Lipolysis by Failing to Sequester the Adipose Triglyceride Lipase (ATGL) Coactivator AB-hydrolase-containing 5 (ABHD5)
por: Gandotra, Sheetal, et al.
Publicado: (2011)

The vesicular transporter STX11 governs ATGL-mediated hepatic lipolysis and lipophagy
por: Zhang, Gaojian, et al.
Publicado: (2022)

ATGL is a biosynthetic enzyme for fatty acid esters of hydroxy fatty acids
por: Patel, Rucha, et al.
Publicado: (2022)

N-end Rule–Mediated Proteasomal Degradation of ATGL Promotes Lipid Storage
por: Xu, Jiesi, et al.
Publicado: (2023)

Higher Levels of ATGL Are Associated with Exercise-Induced Enhancement of Lipolysis in Rat Epididymal Adipocytes
por: Ogasawara, Junetsu, et al.
Publicado: (2012)

ATGL/CGI-58-Dependent Hydrolysis of a Lipid Storage Pool in Murine Enterocytes
por: Korbelius, Melanie, et al.
Publicado: (2019)

The ATGL lipase cooperates with ABHD5 to mobilize lipids for hepatitis C virus assembly
por: Vieyres, Gabrielle, et al.
Publicado: (2020)

Adipose‐specific ATGL ablation reduces burn injury‐induced metabolic derangements in mice
por: Kaur, Supreet, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_9pvc94jq0hr9m1ve18k3i5to93