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Atypical primary hyperparathyroidism due to parathyroid lipoadenoma: a case report

Parathyroid lipoadenoma is a very rare cause of primary hyperparathyroidism. Preoperative imaging techniques often fail to detect such lesions, and even during surgery they can be misinterpreted just as fat tissue. A 62-year-old woman clinically monitored for primary hyperparathyroidism, with hypert...

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Autores principales: Cammarata, Francesco, Yakushkina, Al’ona, Pennacchi, Luca, Carsana, Luca, Zerbi, Pietro, Montecamozzo, Giulio, Danelli, Piergiorgio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8302074/
https://www.ncbi.nlm.nih.gov/pubmed/34316347
http://dx.doi.org/10.1093/jscr/rjab308
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author Cammarata, Francesco
Yakushkina, Al’ona
Pennacchi, Luca
Carsana, Luca
Zerbi, Pietro
Montecamozzo, Giulio
Danelli, Piergiorgio
author_facet Cammarata, Francesco
Yakushkina, Al’ona
Pennacchi, Luca
Carsana, Luca
Zerbi, Pietro
Montecamozzo, Giulio
Danelli, Piergiorgio
author_sort Cammarata, Francesco
collection PubMed
description Parathyroid lipoadenoma is a very rare cause of primary hyperparathyroidism. Preoperative imaging techniques often fail to detect such lesions, and even during surgery they can be misinterpreted just as fat tissue. A 62-year-old woman clinically monitored for primary hyperparathyroidism, with hypertension and a left nephrectomy for hydrouretheronephrosis caused by recurrent kidney stones. A neck ultrasound showed a nodule consistent with left parathyroid of 9 × 5 mm, which was not confirmed on single-photon-emission computed tomography/computed tomography (CT) scan. On surgery, a voluminous lesion with adipose appearance and texture was removed. Frozen sections and intraoperative parathyroid hormone (PTH) confirmed such lesion to be a parathyroid lipoadenoma. Parathyroid lipoadenomas are difficult to localize preoperatively. Sometimes they can be seen by ultrasound scan as hyperechoich lesion, but scintigraphy and CT often fail to identify them. Only the awareness of such lesions and the use of intraoperative PTH can avoid unnecessary extensive cervical exploration.
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spelling pubmed-83020742021-07-26 Atypical primary hyperparathyroidism due to parathyroid lipoadenoma: a case report Cammarata, Francesco Yakushkina, Al’ona Pennacchi, Luca Carsana, Luca Zerbi, Pietro Montecamozzo, Giulio Danelli, Piergiorgio J Surg Case Rep Case Report Parathyroid lipoadenoma is a very rare cause of primary hyperparathyroidism. Preoperative imaging techniques often fail to detect such lesions, and even during surgery they can be misinterpreted just as fat tissue. A 62-year-old woman clinically monitored for primary hyperparathyroidism, with hypertension and a left nephrectomy for hydrouretheronephrosis caused by recurrent kidney stones. A neck ultrasound showed a nodule consistent with left parathyroid of 9 × 5 mm, which was not confirmed on single-photon-emission computed tomography/computed tomography (CT) scan. On surgery, a voluminous lesion with adipose appearance and texture was removed. Frozen sections and intraoperative parathyroid hormone (PTH) confirmed such lesion to be a parathyroid lipoadenoma. Parathyroid lipoadenomas are difficult to localize preoperatively. Sometimes they can be seen by ultrasound scan as hyperechoich lesion, but scintigraphy and CT often fail to identify them. Only the awareness of such lesions and the use of intraoperative PTH can avoid unnecessary extensive cervical exploration. Oxford University Press 2021-07-23 /pmc/articles/PMC8302074/ /pubmed/34316347 http://dx.doi.org/10.1093/jscr/rjab308 Text en Published by Oxford University Press and JSCR Publishing Ltd. © The Author(s) 2021. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Cammarata, Francesco
Yakushkina, Al’ona
Pennacchi, Luca
Carsana, Luca
Zerbi, Pietro
Montecamozzo, Giulio
Danelli, Piergiorgio
Atypical primary hyperparathyroidism due to parathyroid lipoadenoma: a case report
title Atypical primary hyperparathyroidism due to parathyroid lipoadenoma: a case report
title_full Atypical primary hyperparathyroidism due to parathyroid lipoadenoma: a case report
title_fullStr Atypical primary hyperparathyroidism due to parathyroid lipoadenoma: a case report
title_full_unstemmed Atypical primary hyperparathyroidism due to parathyroid lipoadenoma: a case report
title_short Atypical primary hyperparathyroidism due to parathyroid lipoadenoma: a case report
title_sort atypical primary hyperparathyroidism due to parathyroid lipoadenoma: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8302074/
https://www.ncbi.nlm.nih.gov/pubmed/34316347
http://dx.doi.org/10.1093/jscr/rjab308
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