Endothelial Function and Oxidative Stress in X-Linked, gp91(phox) Deficiency, Chronic Granulomatous Disease

Two patients with X-linked chronic granulomatous disease without NAPDH oxidase activity and with high responses of flow-mediated vasodilation are reported. Bone marrow transplantation restored oxidative stress to the levels of those in healthy subjects and decreased flow-mediated vasodilation to the...

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Detalles Bibliográficos
Autores principales: Higashi, Yukihito, Kishimoto, Shinji, Maruhashi, Tatsuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Mini-Focus Issue: Heart Failure
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8302114/
https://www.ncbi.nlm.nih.gov/pubmed/34317001
http://dx.doi.org/10.1016/j.jaccas.2020.05.086
Descripción
Sumario:Two patients with X-linked chronic granulomatous disease without NAPDH oxidase activity and with high responses of flow-mediated vasodilation are reported. Bone marrow transplantation restored oxidative stress to the levels of those in healthy subjects and decreased flow-mediated vasodilation to the levels of those in healthy subjects in both of the patients. (Level of Difficulty: Advanced.)

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