Functional impact of cancer patient‐associated Bcl‐xL mutations

Bcl‐xL, an antiapoptotic protein, is frequently overexpressed in cancer to promote survival of tumor cells. However, we have previously shown that Bcl‐xL promotes migration, invasion, and metastasis independent of its antiapoptotic function in mitochondria. The pro‐metastatic function of Bcl‐xL may...

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Detalles Bibliográficos
Autores principales: Zhang, Tiantian, Na, Joseph HyungJoon, Li, Samantha, Chen, Zhengming, Zhang, George, Pang, Sharon, Daniyan, Anthony F., Li, Yi, Shi, Lei, Du, Yi‐Chieh Nancy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8302207/
https://www.ncbi.nlm.nih.gov/pubmed/34308416
http://dx.doi.org/10.1002/mco2.36

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8302207/
https://www.ncbi.nlm.nih.gov/pubmed/34308416
http://dx.doi.org/10.1002/mco2.36

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