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SARS-CoV-2 activates lung epithelial cell proinflammatory signaling and leads to immune dysregulation in COVID-19 patients

BACKGROUND: The outbreak of Coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 infection has become a global health emergency. We aim to decipher SARS-CoV-2 infected cell types, the consequent host immune response and their interplay in lung of COVID-19 patients. METHODS: We analyzed single-ce...

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Detalles Bibliográficos
Autores principales: Chen, Huarong, Liu, Weixin, Wang, Yifei, Liu, Dabin, Zhao, Liuyang, Yu, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8302220/
https://www.ncbi.nlm.nih.gov/pubmed/34311326
http://dx.doi.org/10.1016/j.ebiom.2021.103500