Data‐driven personalization of a physiologically based pharmacokinetic model for caffeine: A systematic assessment

Physiologically based pharmacokinetic (PBPK) models have been proposed as a tool for more accurate individual pharmacokinetic (PK) predictions and model‐informed precision dosing, but their application in clinical practice is still rare. This study systematically assesses the benefit of using indivi...

Descripción completa

Detalles Bibliográficos
Autores principales: Fendt, Rebekka, Hofmann, Ute, Schneider, Annika R. P., Schaeffeler, Elke, Burghaus, Rolf, Yilmaz, Ali, Blank, Lars Mathias, Kerb, Reinhold, Lippert, Jörg, Schlender, Jan‐Frederik, Schwab, Matthias, Kuepfer, Lars
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8302243/
https://www.ncbi.nlm.nih.gov/pubmed/34053199
http://dx.doi.org/10.1002/psp4.12646

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8302243/
https://www.ncbi.nlm.nih.gov/pubmed/34053199
http://dx.doi.org/10.1002/psp4.12646

Ejemplares similares